Methyl (2-{4-[(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetate | CAS No. 83881-46-3

Methyl (2-{4-[(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetate

Basic Information

CAS Number

83881-46-3

Molecular Formula

C22H27ClN2O3

Molecular Weight

402.92 g/mol

AD

Basic Physical Properties

COC(=O)COCCN1CCN(CC1)C(c2ccccc2)c3ccc(cc3)Cl

InChI

InChI=1S/C22H27ClN2O3/c1-27-21(26)17-28-16-15-24-11-13-25(14-12-24)22(18-5-3-2-4-6-18)19-7-9-20(23)10-8-19/h2-10,22H,11-17H2,1H3

InChIKey

BYCHNMFDSQCCDD-UHFFFAOYSA-N

LogP

3.236600000000003

Topological Polar Surface Area

42.010000000000005 Ų

Hydrogen Bond Donor/Acceptor

0 / 5

Synonyms & References

English

  • Acetic acid,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, methyl ester
  • Cetirizine Methyl Ester
  • Cetirizine Methyl Ester (Discontinued, See C291140 dihydrochloride)
  • Cetirizine Methyl Ester (Discontinued, See C291140 dihydrochloride)
  • methyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate
  • methyl 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetate
  • (2-{4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl}ethoxy)acetic acid methyl ester
  • Cetirizine Methanol Adduct
  • methyl [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetate
  • methyl-2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetate

MDL Number

MFCD18252586

FAQ

What regulatory guidelines apply to Methyl (2-{4-[(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetate (CAS: 83881-46-3)?

Methyl (2-{4-[(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetate (CAS: 83881-46-3) falls under the scope of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) and is classified as a hazardous substance based on its potential health and environmental impacts. Additionally, it must comply with the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulations in the European Union, which require detailed safety data sheets (SDS) and risk management information. In the United States, the Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) mandate compliance with specific handling and disposal requirements to ensure worker safety and environmental protection.

Are there alternatives to Methyl (2-{4-[(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetate (CAS: 83881-46-3) in synthesis?

There are several alternatives to Methyl (2-{4-[(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetate (CAS: 83881-46-3) in synthesis, including the use of related piperazine derivatives or other acylating agents that can serve similar functional roles in organic chemistry. Common alternatives include 4-(phenylmethyl)piperazine-1-carboxylic acid, which can be used to create similar ether structures through esterification and acylation processes. These alternatives can offer similar reactivity and functionality but may have different handling and regulatory requirements.

What is the market or research trend for Methyl (2-{4-[(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetate (CAS: 83881-46-3)?

The market and research trends for Methyl (2-{4-[(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetate (CAS: 83881-46-3) are primarily driven by its use in pharmaceuticals and fine chemicals. Recent research has focused on optimizing synthetic methods and exploring its potential in drug discovery and development. Market trends indicate increasing demand in the pharmaceutical industry, particularly for novel therapeutics targeting specific diseases. The trend is also towards more sustainable and environmentally friendly synthesis methods to meet regulatory and ethical standards.

How should waste containing Methyl (2-{4-[(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetate (CAS: 83881-46-3) be handled?

Waste containing Methyl (2-{4-[(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)acetate (CAS: 83881-46-3) should be collected in appropriate, labeled containers and stored in a well-ventilated area away from sources of ignition and incompatible materials. For safe disposal, consult the material safety data sheet (MSDS) and follow local, state, and federal regulations regarding hazardous waste management. Typically, professional waste disposal services should be utilized to ensure compliance with environmental protection standards. Proper incineration in a licensed facility or chemical recycling processes may be necessary to manage the waste effectively while minimizing environmental impact.

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