Bis(2-hydroxyphenyl)methanone

Basic Information

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CAS Number

835-11-0

Molecular Formula

C13H10O3

Molecular Weight

214.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

61.0 to 64.0 deg-C

Boiling Point

333°C (estimate)

Density

1.1956 (rough estimate)

Flash Point

166.8°C

Refractive Index

1.5090 (estimate)

SMILES

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Oc1ccccc1C(=O)c1ccccc1O

InChI

InChI=1S/C13H10O3/c14-11-7-3-1-5-9(11)13(16)10-6-2-4-8-12(10)15/h1-8,14-15H

InChIKey

YIYBRXKMQFDHSM-UHFFFAOYSA-N

LogP

2.3288000000000006

Topological Polar Surface Area

57.53 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

228

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

2,2 -Dihydroxybenzophenone
2,2'-Dihydroxybenzophenone
2.2'-Dihydroxybenzophenone
Bis(2-hydroxyphenyl)methanone

MDL Number

MFCD00002217

Customs Code

2914501900

FAQ

What are the physical and chemical properties of Bis(2-hydroxyphenyl)methanone (CAS: 835-11-0)?

Bis(2-hydroxyphenyl)methanone (CAS: 835-11-0) is a white to off-white solid with a molecular weight of approximately 228.14 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is a ketone with two hydroxyl groups attached to the aromatic rings. It is relatively stable but can undergo hydrolysis under basic conditions. It shows moderate reactivity with nucleophiles and electrophiles, making it useful in various chemical reactions.

How is Bis(2-hydroxyphenyl)methanone (CAS: 835-11-0) typically synthesized?

Bis(2-hydroxyphenyl)methanone is typically synthesized through the condensation of two equivalents of 2-hydroxybenzaldehyde using a coupling agent like triphenylphosphine in the presence of sodium hydroxide. This method provides good yield and selectivity. Other methods include the reaction of phenol with formaldehyde followed by oxidation, although this route is less common and less efficient.

What industries use Bis(2-hydroxyphenyl)methanone (CAS: 835-11-0)?

Bis(2-hydroxyphenyl)methanone (CAS: 835-11-0) is used in various industries. It is a key intermediate in the production of UV absorbers for the pharmaceutical and cosmetic industries. It is also used in the synthesis of polymers, particularly for thermosetting resins. Additionally, it finds applications in the development of sensors and semiconductors due to its photochemical and thermal properties.

What precautions should be taken when handling Bis(2-hydroxyphenyl)methanone (CAS: 835-11-0)?

When handling Bis(2-hydroxyphenyl)methanone (CAS: 835-11-0), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risks. If a spill occurs, immediately clean it up using appropriate absorbent materials and follow standard laboratory procedures for chemical spills. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency response guidelines.