Bis(2-hydroxyphenyl)methanone(CAS: 835-11-0)

Bis(2-hydroxyphenyl)methanone (CAS: 835-11-0) is a white to off-white solid with a molecular weight of approximately 228.14 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is a ketone with two hydroxyl groups attached to the aromatic rings. It is relatively stable but can undergo hydrolysis under basic conditions. It shows moderate reactivity with nucleophiles and electrophiles, making it useful in various chemical reactions.

Bis(2-hydroxyphenyl)methanone is typically synthesized through the condensation of two equivalents of 2-hydroxybenzaldehyde using a coupling agent like triphenylphosphine in the presence of sodium hydroxide. This method provides good yield and selectivity. Other methods include the reaction of phenol with formaldehyde followed by oxidation, although this route is less common and less efficient.

Bis(2-hydroxyphenyl)methanone (CAS: 835-11-0) is used in various industries. It is a key intermediate in the production of UV absorbers for the pharmaceutical and cosmetic industries. It is also used in the synthesis of polymers, particularly for thermosetting resins. Additionally, it finds applications in the development of sensors and semiconductors due to its photochemical and thermal properties.

When handling Bis(2-hydroxyphenyl)methanone (CAS: 835-11-0), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risks. If a spill occurs, immediately clean it up using appropriate absorbent materials and follow standard laboratory procedures for chemical spills. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency response guidelines.