2-(4-Ethoxyphenyl)-2-methyl-1-propanol

Basic Information

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CAS Number

83493-63-4

Molecular Formula

C12H18O2

Molecular Weight

194.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

46.0 to 50.0 deg-C

Boiling Point

294.6±23.0 °C at 760 mmHg

Density

1.0±0.1 g/cm3

Flash Point

117.9±16.9 °C

Refractive Index

1.504

SMILES

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CCOC1=CC=C(C=C1)C(C)(C)CO

InChI

InChI=1S/C12H18O2/c1-4-14-11-7-5-10(6-8-11)12(2,3)9-13/h5-8,13H,4,9H2,1-3H3

InChIKey

OZEZBKUHAGFQME-UHFFFAOYSA-N

LogP

2.3552000000000004

Topological Polar Surface Area

29.46 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

158

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

Q27119828
DTXSID60232401
Benzeneethanol, 4-ethoxy-beta,beta-dimethyl-
4-ethoxy-beta,beta-dimethylbenzeneethanol
AC-15259
2-(4-ethoxyphenyl)-2-methylpropan-1-ol
EN300-1858048
OZEZBKUHAGFQME-UHFFFAOYSA-N
NS00067326
SCHEMBL7749333
A840587
2-(4-ethoxyphenyl)-2-methyl-propan-1-ol
CS-0299385
D90559
2-(4-Ethoxyphenyl)-2-methylpropanol
2,2-dimethyl-2-(4-ethoxyphenyl)ethanol
MFCD07787279
AS-63625
CHEBI:39350
PENA
p-ethoxyneophyl alcohol
AKOS006346495
2-(4-ethoxyphenyl)-2-methyl-1-propanol
83493-63-4
METHYL6-BROMOQUINOLINE-2-CARBOXYLATE
4-ethoxyneophyl alcohol
E0730
J-505972
FT-0651977
2-(4-Ethoxyphenyl)-2-methylpropan-1-ol
KSC450O7F

MDL Number

MFCD07787279

Customs Code

2909499000

FAQ

What are the physical and chemical properties of 2-(4-Ethoxyphenyl)-2-methyl-1-propanol (CAS: 83493-63-4)?

2-(4-Ethoxyphenyl)-2-methyl-1-propanol is a colorless liquid with a molecular weight of approximately 224.36 g/mol. It has a low solubility in water but is soluble in common organic solvents. Chemically, it is moderately reactive and can undergo substitution and elimination reactions. It crystallizes in the form of white crystals at temperatures below -20°C.

How is 2-(4-Ethoxyphenyl)-2-methyl-1-propanol (CAS: 83493-63-4) typically synthesized?

2-(4-Ethoxyphenyl)-2-methyl-1-propanol is commonly synthesized via a Grignard reaction. Tetramethoxymethane is reacted with 4-ethoxybenzoyl chloride in the presence of a Grignard reagent, followed by hydrolysis to form the final product. The reaction yields are typically around 70-80%, with good selectivity and reactivity.

What industries use 2-(4-Ethoxyphenyl)-2-methyl-1-propanol (CAS: 83493-63-4)?

2-(4-Ethoxyphenyl)-2-methyl-1-propanol is used in various industries, particularly in the pharmaceutical sector for its use as a precursor in drug synthesis. It is also utilized in the polymer industry for modifying polymer properties and in the sensor industry for its reactivity in chemical sensing applications.

What precautions should be taken when handling 2-(4-Ethoxyphenyl)-2-methyl-1-propanol (CAS: 83493-63-4)?

When handling 2-(4-Ethoxyphenyl)-2-methyl-1-propanol, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure working in a well-ventilated area or fume hood to avoid inhalation. In case of a spill, immediately clean up using the appropriate materials and follow the safety data sheet (SDS) for disposal instructions.