Compound Q&A

How is 2-(4-Ethoxyphenyl)-2-methyl-1-propanol (CAS: 83493-63-4) typically synthesized?

Answer

2-(4-Ethoxyphenyl)-2-methyl-1-propanol
2-(4-Ethoxyphenyl)-2-methyl-1-propanol is commonly synthesized via a Grignard reaction. Tetramethoxymethane is reacted with 4-ethoxybenzoyl chloride in the presence of a Grignard reagent, followed by hydrolysis to form the final product. The reaction yields are typically around 70-80%, with good selectivity and reactivity.

About

CAS No 83493-63-4
English Name 2-(4-Ethoxyphenyl)-2-methyl-1-propanol
Molecular Formula C12H18O2
Molecular Weight 194.27 g/mol
SMILES CCOC1=CC=C(C=C1)C(C)(C)CO
InChIKey OZEZBKUHAGFQME-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24

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