3,5-Dichloro-2,4-difluoroaniline

Basic Information

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CAS Number

83121-15-7

Molecular Formula

C6H3Cl2F2N

Molecular Weight

198 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

72.0 to 77.0 deg-C

SMILES

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C1=C(C(=C(C(=C1Cl)F)Cl)F)N

InChI

InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2

InChIKey

KLECNQGLBJHVSH-UHFFFAOYSA-N

LogP

2.8537999999999997

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

147

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

SCHEMBL796071
NS00014270
Benzenamine, 3,5-dichloro-2,4-difluoro-
AC-3674
EN300-6452609
83121-15-7
AKOS006229005
C6H3Cl2F2N
D78090
2,4-Difluoro-3,5-dichloroaniline
2,4-Difluoro-3,5-dichloro aniline
3,5-dichloro-2,4-difluoro-aniline
MFCD00044104
FT-0601460
D3637
AM62112
3,5-Dichloro-2,4-Difluoro-Benzenamine
3,5-Dichloro-2,4-difluoroaniline
DTXSID90378826
J-507199
AS-15715
KLECNQGLBJHVSH-UHFFFAOYSA-N
3,5-dichloro-2,4-difluorobenzenamine
2,4-DIFLUORO-3,5-DICHLORANILINE
2,4-DIFLUORO-3,5-DICHLORO ANILINE
3,5-Dichloro-2,4-Difluoro-BenzenaMine

MDL Number

MFCD00044104

Customs Code

2921420090

FAQ

What are the physical and chemical properties of 3,5-Dichloro-2,4-difluoroaniline (CAS: 83121-15-7)?

3,5-Dichloro-2,4-difluoroaniline is a solid with a crystalline form. It has a molecular weight of approximately 246.01 g/mol and a melting point of 105-106°C. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound is reactive and can undergo substitution reactions. It is often used in the synthesis of other compounds and pharmaceuticals.

How is 3,5-Dichloro-2,4-difluoroaniline (CAS: 83121-15-7) typically synthesized?

3,5-Dichloro-2,4-difluoroaniline is typically synthesized through the Claisen rearrangement of 4-chloro-2,6-difluorophenylamine. This involves the use of a base such as sodium hydroxide and a solvent like methanol. The reaction is carried out at room temperature, and the product can be isolated by filtration and recrystallization. The yield is generally around 75-80%.

What industries use 3,5-Dichloro-2,4-difluoroaniline (CAS: 83121-15-7)?

3,5-Dichloro-2,4-difluoroaniline (CAS: 83121-15-7) is used in various industries. It is primarily used in the pharmaceutical industry as a precursor for the synthesis of drugs. It is also used in the production of dyes and pigments, as well as in the development of sensors and semiconductors.

What precautions should be taken when handling 3,5-Dichloro-2,4-difluoroaniline (CAS: 83121-15-7)?

When handling 3,5-Dichloro-2,4-difluoroaniline (CAS: 83121-15-7), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be carefully cleaned up using appropriate spill control materials. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and disposal.