Compound Q&A
How is 3,5-Dichloro-2,4-difluoroaniline (CAS: 83121-15-7) typically synthesized?
Answer
3,5-Dichloro-2,4-difluoroaniline is typically synthesized through the Claisen rearrangement of 4-chloro-2,6-difluorophenylamine. This involves the use of a base such as sodium hydroxide and a solvent like methanol. The reaction is carried out at room temperature, and the product can be isolated by filtration and recrystallization. The yield is generally around 75-80%.
About
CAS No
83121-15-7
English Name
3,5-Dichloro-2,4-difluoroaniline
Molecular Formula
C6H3Cl2F2N
Molecular Weight
198 g/mol
SMILES
C1=C(C(=C(C(=C1Cl)F)Cl)F)N
InChIKey
KLECNQGLBJHVSH-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53
