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3,5-Dichloro-2,4-difluoroaniline(CAS: 83121-15-7)

3,5-Dichloro-2,4-difluoroaniline
CAS Number

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Basic Information

Molecular Formula
C6H3Cl2F2N
Molecular Weight
198 g/mol

Physical Properties

Melting Point
72.0 to 77.0 deg-C

Chemical Identifiers

SMILES
C1=C(C(=C(C(=C1Cl)F)Cl)F)N
InChIKey
KLECNQGLBJHVSH-UHFFFAOYSA-N

Database References

MDL Number
MFCD00044104

FAQ

3,5-Dichloro-2,4-difluoroaniline is a solid with a crystalline form. It has a molecular weight of approximately 246.01 g/mol and a melting point of 105-106°C. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound is reactive and can undergo substitution reactions. It is often used in the synthesis of other compounds and pharmaceuticals.
3,5-Dichloro-2,4-difluoroaniline is typically synthesized through the Claisen rearrangement of 4-chloro-2,6-difluorophenylamine. This involves the use of a base such as sodium hydroxide and a solvent like methanol. The reaction is carried out at room temperature, and the product can be isolated by filtration and recrystallization. The yield is generally around 75-80%.
3,5-Dichloro-2,4-difluoroaniline (CAS: 83121-15-7) is used in various industries. It is primarily used in the pharmaceutical industry as a precursor for the synthesis of drugs. It is also used in the production of dyes and pigments, as well as in the development of sensors and semiconductors.
When handling 3,5-Dichloro-2,4-difluoroaniline (CAS: 83121-15-7), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be carefully cleaned up using appropriate spill control materials. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and disposal.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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