5-(2-furyl)pyrazin-2-ol

Basic Information

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CAS Number

82619-62-3

Molecular Formula

C8H6N2O2

Molecular Weight

162.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

466.317°C at 760 mmHg

Density

1.325

Flash Point

235.821°C

Refractive Index

1.588

SMILES

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C1=COC(=C1)C2=CNC(=O)C=N2

InChI

InChI=1S/C8H6N2O2/c11-8-5-9-6(4-10-8)7-2-1-3-12-7/h1-5H,(H,10,11)

InChIKey

UGVAWFFQXFNGDS-UHFFFAOYSA-N

LogP

1.4421999999999995

Topological Polar Surface Area

59.150000000000006 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

258

Synonyms & References

English

5-FURAN-2-YL-PYRAZIN-2-OL
5-(2-FURYL)-2(1H)-PYRAZINONE
GS-6173
FT-0739802
A922898
AKOS006291064
5-(2-Furyl)-2-hydroxypyrazine
AKOS005255853
5-(Furan-2-yl)pyrazin-2-ol
DTXSID70509232
82619-62-3
5-Furan-2-yl-1H-pyrazin-2-one
SY058542
5-(Furan-2-yl)-1,2-dihydropyrazin-2-one
5-(Furan-2-yl)pyrazin-2(1H)-one
O=C1NC=C(N=C1)C1=CC=CO1
SCHEMBL2915360
MFCD09033267
5-(furan-2-yl)-1H-pyrazin-2-one
UGVAWFFQXFNGDS-UHFFFAOYSA-N
H10188
MFCD09027874
2(1H)-Pyrazinone,5-(2-furanyl)-
5-FURAN-2-YL-1H-PYRAZIN-2-ONE

MDL Number

MFCD09033267

FAQ

What are the physical and chemical properties of 5-(2-furyl)pyrazin-2-ol (CAS: 82619-62-3)?

5-(2-furyl)pyrazin-2-ol is a crystalline solid with a molecular weight of approximately 170.14 g/mol. It has a pKa of around 6.3 and is slightly soluble in water. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is also prone to undergo elimination reactions under certain conditions.

How is 5-(2-furyl)pyrazin-2-ol (CAS: 82619-62-3) typically synthesized?

5-(2-furyl)pyrazin-2-ol is typically synthesized through a multistep process involving the reaction of 2-furylmethylamine with 2-hydroxypyrazine. The synthesis involves condensation reactions and typically uses basic conditions. The yield is generally around 70-80%, and the selectivity towards the desired product is high.

What industries use 5-(2-furyl)pyrazin-2-ol (CAS: 82619-62-3)?

5-(2-furyl)pyrazin-2-ol is used in various industries, particularly in pharmaceuticals where it serves as a precursor for the synthesis of other compounds. It is also utilized in the production of dyes and polymers due to its aromatic structure. Additionally, it is employed in the development of sensors and semiconductors for its electronic properties.

What precautions should be taken when handling 5-(2-furyl)pyrazin-2-ol (CAS: 82619-62-3)?

When handling 5-(2-furyl)pyrazin-2-ol, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Refer to the Material Safety Data Sheet (MSDS) for detailed information on handling and storage.