5-(2-furyl)pyrazin-2-ol(CAS: 82619-62-3)

5-(2-furyl)pyrazin-2-ol is a crystalline solid with a molecular weight of approximately 170.14 g/mol. It has a pKa of around 6.3 and is slightly soluble in water. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is also prone to undergo elimination reactions under certain conditions.

5-(2-furyl)pyrazin-2-ol is typically synthesized through a multistep process involving the reaction of 2-furylmethylamine with 2-hydroxypyrazine. The synthesis involves condensation reactions and typically uses basic conditions. The yield is generally around 70-80%, and the selectivity towards the desired product is high.

5-(2-furyl)pyrazin-2-ol is used in various industries, particularly in pharmaceuticals where it serves as a precursor for the synthesis of other compounds. It is also utilized in the production of dyes and polymers due to its aromatic structure. Additionally, it is employed in the development of sensors and semiconductors for its electronic properties.

When handling 5-(2-furyl)pyrazin-2-ol, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Refer to the Material Safety Data Sheet (MSDS) for detailed information on handling and storage.