Mecamylamine hydrochloride

Basic Information

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CAS Number

826-39-1

Molecular Formula

C11H22ClN

Molecular Weight

203.76 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

266-267°C

Boiling Point

189.3 °C at 760 mmHg

Flash Point

58.1 °C

Solubility

ethanol: 122 mg/mL

SMILES

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CC1(C2CCC(C2)C1(C)NC)C.Cl

InChI

InChI=1S/C11H21N.ClH/c1-10(2)8-5-6-9(7-8)11(10,3)12-4;/h8-9,12H,5-7H2,1-4H3;1H

InChIKey

PKVZBNCYEICAQP-UHFFFAOYSA-N

LogP

2.8424000000000014

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

197

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

Mekamin hydrochloride
N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine;hydrochloride
3-Methylaminoisocamphane hydrochloride
4956DJR58O
2-(Methylamino)-2,3,3-trimethylnorbornane hydrochloride
Mecamylamine, HCl
Mecamylamine hydrochloride 100 microg/mL in Acetonitrile
NCGC00094171-01
Norbornane, 2-(methylamino)-2,3,3-trimethyl-, hydrochloride
NSC-757086
M 9020
FT-0603516
826-39-1
EU-0100841
2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
3-Methylaminoisokamfan chlorid
Bicyclo[2.2.1]heptan-2-amine, N,2,3,3-tetramethyl-, hydrochloride (1:1)
SR-01000075329
CS-0013122
Mecamylamine hydrochloride (USP)
inversin
2-(Methylamino)isocamphane hydrochloride
NSC757086
UNII-4956DJR58O
Q27259230
AGI-004
Mecamylamine (hydrochloride)
Inversine
Vecamyl
HY-B1395
N,2,3,3-tetramethyl-2-norcamphanamine hydrochloride

MDL Number

MFCD00151462

Customs Code

2921300090

FAQ

What regulatory guidelines apply to mecamylamine hydrochloride (CAS: 826-39-1)?

Mecamylamine hydrochloride (CAS: 826-39-1) falls under the regulatory guidelines of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which includes classification as a toxic substance. In the European Union, it is also subject to the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulation. In the United States, it is regulated by the Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) for safety and environmental impact.

Are there alternatives to mecamylamine hydrochloride (CAS: 826-39-1) in synthesis?

There are several alternatives to mecamylamine hydrochloride (CAS: 826-39-1) in synthesis, including analogs like chlorisondamine and analogs with similar pharmacological properties. Common alternative reagents in synthesis include other cholinergic receptor antagonists such as tubocurarine and d-tubocurarine. These alternatives offer similar functionalities but may have different physical and chemical properties, making them suitable for specific applications.

What is the market or research trend for mecamylamine hydrochloride (CAS: 826-39-1)?

The market for mecamylamine hydrochloride (CAS: 826-39-1) has shown steady growth due to its application in treating certain medical conditions, particularly in the field of neurology. Research trends are focusing on understanding its mechanisms of action, potential as an adjuvant in cancer therapy, and exploring its use in treating neurological disorders. Additionally, there is interest in developing more specific and potent analogs to reduce side effects.

How should waste containing mecamylamine hydrochloride (CAS: 826-39-1) be handled?

Waste containing mecamylamine hydrochloride (CAS: 826-39-1) should be collected in appropriate containers and stored away from incompatible materials. Proper disposal methods include incineration or professional waste disposal services that can handle hazardous substances. Environmental protection precautions include ensuring that disposal methods comply with local and national regulations to prevent contamination of soil and water. It is crucial to follow safety guidelines and use personal protective equipment during handling and disposal.