3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride | CAS No. 82205-57-0

3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride

Basic Information

CAS Number

82205-57-0

Molecular Formula

C10H17ClN4

Molecular Weight

228.72 g/mol

AD

Basic Physical Properties

CN1CCN(CC1)C2=NC=C(C=C2)N.Cl

InChI

InChI=1S/C10H16N4.ClH/c1-13-4-6-14(7-5-13)10-3-2-9(11)8-12-10;/h2-3,8H,4-7,11H2,1H3;1H

InChIKey

UHNLDLCXUNIOJX-UHFFFAOYSA-N

LogP

0.8373999999999997

Topological Polar Surface Area

45.39 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

177

Synonyms & References

English

  • 6-(4-methylpiperazin-1-yl)pyridin-3-amine hydrochloride
  • AC6873
  • 3-amino-6-(4-Methyl-1-piperazinyl) pyridine hydrochloride
  • 82205-57-0
  • 3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride
  • AKOS022183467
  • SCHEMBL15112630
  • AC-26861
  • A864441
  • MFCD11052569
  • 6-(4-methyl-1-piperazinyl)-3-pyridinamine hydrochloride
  • 6-(4-methylpiperazin-1-yl)pyridin-3-amine HCl
  • 6-(4-methylpiperazin-1-yl)pyridin-3-amine;hydrochloride
  • DTXSID50697348
  • AMY20249
  • 6-(4-methylpiperazin-1-yl)pyridin-3-aminehydrochloride
  • 3-Amino-6-(4-methyl-1-piperazinyl)pyridine Hydrochloride
  • 6-(4-Methylpiperazin-1-yl)pyridin-3-amine--hydrogen chloride (1/1)
  • SY003476
  • 1234971-67-5
  • UHNLDLCXUNIOJX-UHFFFAOYSA-N
  • 6-(4-Methylpiperazin-1-yl)pyridin-3-amine hydrochloride
  • 3-Amino-6-(4-methyl-1-piperazinyl)pyridine diHydrochloride
  • 3-AMINO-6-(4-METHYL-1-PIPERAZINYL)PYRIDINE HYDROCHLORIDE
  • 3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride

MDL Number

MFCD11052569

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride (CAS: 82205-57-0)?

3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride (CAS: 82205-57-0) is a white crystalline solid with a molecular weight of approximately 338.4 g/mol. It has a high solubility in water and is sparingly soluble in ethanol. This compound is relatively stable under normal conditions but is reactive towards bases and undergoes hydrolysis. It is commonly used as a salt in pharmaceutical applications.

How is 3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride (CAS: 82205-57-0) typically synthesized?

3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride (CAS: 82205-57-0) is synthesized by the reaction of 3-chloro-6-(4-methylpiperazin-1-yl)pyridine with hydrochloric acid. The reaction is performed under mild conditions and typically involves the substitution of the chlorine atom with a hydrochloride ion. The yield is around 90%, and the reaction is highly selective.

What industries use 3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride (CAS: 82205-57-0)?

3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride (CAS: 82205-57-0) is primarily used in the pharmaceutical industry for the development of novel drug candidates. It is also used in the synthesis of certain polymers and as a precursor in the production of sensors and semiconductors.

What precautions should be taken when handling 3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride (CAS: 82205-57-0)?

When handling 3-Amino-6-(4-methylpiperazin-1-yl)pyridine triHydrochloride (CAS: 82205-57-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. It is recommended to consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...