Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate | CAS No. 82101-18-6

Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate

Basic Information

CAS Number

82101-18-6

Molecular Formula

C17H13N3Na2O6

Molecular Weight

401.28 g/mol

AD

Basic Physical Properties

Boiling Point

°Cat760mmHg

C1=CC(=CC=C1C(=O)NCCC(=O)[O-])N=NC2=CC(=C(C=C2)[O-])C(=O)O.[Na+].[Na+]

InChI

InChI=1S/C17H15N3O6.2Na/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;/q;2*+1/p-2/b20-19+;;

InChIKey

CKMOQBVBEGCJGW-LLIZZRELSA-L

LogP

-1.39660

Complexity

539

Synonyms & References

English

  • Balsalazide disodium anhydrous
  • FT-0658348
  • 213594-60-6
  • BENZOIC ACID, 5-((1E)-2-(4-(((2-CARBOXYETHYL)AMINO)CARBONYL)PHENYL)DIAZENYL)-2-HYDROXY-, SODIUM SALT (1:2)
  • CHEMBL1200760
  • HMS3264M06
  • AKOS015896484
  • BALSALAZIDE DISODIUM SALT ANHYDROUS [MI]
  • 82101-18-6
  • AKOS025294907
  • 15ASW03C9S
  • CCG-213078
  • 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic Acid Disodium Salt
  • Balsalazidedisodium
  • BALSALAZIDE SODIUM [WHO-DD]
  • HMS3714A22
  • Balsalazide disodium salt hydrate
  • A815288
  • Sodium (E)-5-((4-((2-carboxylatoethyl)carbamoyl)phenyl)diazenyl)-2-hydroxybenzoate
  • SCHEMBL3666408
  • disodium;3-[[4-[(3-carboxy-4-oxidophenyl)diazenyl]benzoyl]amino]propanoate
  • balsalazine
  • HMS2097A22
  • disodium 3-[[4-[(2-carboxylatoethylamino)-oxomethyl]phenyl]hydrazinylidene]-6-oxo-1-cyclohexa-1,4-dienecarboxylate
  • NSC-760046
  • Balsalazide Disodium
  • BX-661A
  • Balsalazide sodium
  • Balsalazide Disodium Salt
  • Benzoic acid,5-[[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]azo]-2-hydroxy-, disodiumsalt
  • FT-0622551

MDL Number

MFCD01631117

FAQ

What are the physical and chemical properties of Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate (CAS: 82101-18-6)?

Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate is a crystalline compound with a molecular weight of approximately 502.5 g/mol. It has a solubility of about 5 g/L in water. The compound is moderately reactive, showing potential for ester and amide bond formation. It has a pKa of around 4.5, making it mildly acidic.

How is Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate (CAS: 82101-18-6) typically synthesized?

Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate is synthesized via a multi-step process involving the diazotization of a phenol followed by coupling with an amino acid derivative. Commonly, sodium dithionite is used as a reducing agent, and the reaction is typically carried out in an aqueous solution with a high yield of around 85%.

What industries use Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate (CAS: 82101-18-6)?

Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate is used in the pharmaceutical industry for its potential as an intermediate in drug synthesis. It also finds application in the research of sensors and semiconductors due to its photochemical and electronic properties.

What precautions should be taken when handling Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate (CAS: 82101-18-6)?

When handling Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate, it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure the reaction is conducted in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up with appropriate absorbents, and the area should be thoroughly washed down with water. Always refer to the Safety Data Sheet (SDS) for specific guidelines.

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