Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate(CAS: 82101-18-6)

Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate is a crystalline compound with a molecular weight of approximately 502.5 g/mol. It has a solubility of about 5 g/L in water. The compound is moderately reactive, showing potential for ester and amide bond formation. It has a pKa of around 4.5, making it mildly acidic.

Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate is synthesized via a multi-step process involving the diazotization of a phenol followed by coupling with an amino acid derivative. Commonly, sodium dithionite is used as a reducing agent, and the reaction is typically carried out in an aqueous solution with a high yield of around 85%.

Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate is used in the pharmaceutical industry for its potential as an intermediate in drug synthesis. It also finds application in the research of sensors and semiconductors due to its photochemical and electronic properties.

When handling Disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate, it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure the reaction is conducted in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up with appropriate absorbents, and the area should be thoroughly washed down with water. Always refer to the Safety Data Sheet (SDS) for specific guidelines.