4-Phenylthieno[3,2-c]pyridine

Basic Information

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CAS Number

81820-65-7

Molecular Formula

C13H9NS

Molecular Weight

211.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

61-62 ºC

Density

1.231

SMILES

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C1=CC=C(C=C1)C2=NC=CC3=C2C=CS3

InChI

InChI=1S/C13H9NS/c1-2-4-10(5-3-1)13-11-7-9-15-12(11)6-8-14-13/h1-9H

InChIKey

UEXKIEYHNLJFQH-UHFFFAOYSA-N

LogP

3.963300000000002

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

213

Synonyms & References

English

FT-0749946
81820-65-7
SCHEMBL2576162
Thieno[3,2-c]pyridine,4-phenyl-
DTXSID70509555
4-Phenylthieno[3,2-c]pyridine
4-phenyl-Thieno[3,2-c]pyridine
4-Phenyl-thieno<3,2-c>pyridin
Thieno[3,2-c]pyridine,4-phenyl

MDL Number

MFCD13186012

FAQ

What are the physical and chemical properties of 4-Phenylthieno[3,2-c]pyridine (CAS: 81820-65-7)?

4-Phenylthieno[3,2-c]pyridine is a crystalline solid with a molecular weight of approximately 228.25 g/mol. It has low water solubility and moderate solubility in organic solvents such as ethanol and dimethylformamide. This compound exhibits good thermal stability and moderate reactivity towards nucleophiles. It is insoluble in water and miscible with common organic solvents.

How is 4-Phenylthieno[3,2-c]pyridine (CAS: 81820-65-7) typically synthesized?

4-Phenylthieno[3,2-c]pyridine is often synthesized through a multi-step process involving the reaction of a thieno[3,2-c]pyridine derivative with a phenyl Grignard reagent or similar nucleophile. The reaction is typically conducted in an anhydrous, inert atmosphere to prevent side reactions. The yield is generally around 70-80%, with a high degree of selectivity towards the desired product.

What industries use 4-Phenylthieno[3,2-c]pyridine (CAS: 81820-65-7)?

4-Phenylthieno[3,2-c]pyridine is used in the pharmaceutical industry for its potential in developing new drug candidates, particularly in the field of anticancer agents and as a scaffold for medicinal chemistry. It is also utilized in the semiconductor industry due to its electronic properties and in the polymer industry for its potential as a monomer or additive. Additionally, it plays a role in sensors due to its ability to interact with certain molecules and ions.

What precautions should be taken when handling 4-Phenylthieno[3,2-c]pyridine (CAS: 81820-65-7)?

When handling 4-Phenylthieno[3,2-c]pyridine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials, and proper disposal procedures should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.