2-[1-(Tert-butoxycarbonyl)piperidin-4-yl]propanoic acid | CAS No. 815593-60-3
2-[1-(Tert-butoxycarbonyl)piperidin-4-yl]propanoic acid
Basic Information
CAS Number
815593-60-3
Molecular Formula
C13H23NO4
Molecular Weight
257.33 g/mol
AD
Chemical Classification
Basic Physical Properties
Safety Information
View Safety InformationHazard Class
Class IRRITANT
Class IRRITANT
Synonyms & References
English
- 2-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-propanoic acid
- 2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]propanoic acid
- 2-[1-(tert-butoxycarbonyl)piperidin-4-yl]propanoic acid
- FZNNOLMIECALJP-UHFFFAOYSA-N
- 4-Piperidineacetic acid, 1-[(1,1-dimethylethoxy)carbonyl]-
- DB-005694
- 2-(1-Boc-piperidin-4-yl)propionic acid
- A1-08674
- 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)propanoic acid
- AKOS005174403
- 2-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}propanoic acid
- CS-0046902
- 2-[1-(tert-butoxycarbonyl)piperidin-4-yl)propanoic acid
- 815593-60-3
- MFCD15146529
- SCHEMBL1422213
- ALBB-013976
- AS-39695
- 1-boc-piperidine-4-yl-propionic acid
- 4-(1-Carboxy-ethyl)-piperidine-1-carboxylic acid tert-butyl ester
- 4-piperidineacetic acid, 1-[(1,1-dimethylethoxy)carbonyl]-alpha-methyl-
- EN300-783145
- XH1220
MDL Number
MFCD15146529
FAQ
What are the physical and chemical properties of 2-[1-(Tert-butoxycarbonyl)piperidin-4-yl]propanoic acid (CAS: 815593-60-3)?
2-[1-(Tert-butoxycarbonyl)piperidin-4-yl]propanoic acid is a white crystalline solid with a molecular weight of approximately 313.4 g/mol. It has a pKa of about 6.5 and is poorly soluble in water but soluble in most organic solvents. It is reactive towards nucleophiles and can undergo acid-catalyzed esterification.
How is 2-[1-(Tert-butoxycarbonyl)piperidin-4-yl]propanoic acid (CAS: 815593-60-3) typically synthesized?
2-[1-(Tert-butoxycarbonyl)piperidin-4-yl]propanoic acid is typically synthesized via a multi-step process involving the protection of a piperidine ring with tert-butoxycarbonyl followed by functionalization of the alkyl chain. Common reagents include tert-butyloxycarbonyl chloride and various alkyl halides. The reaction is typically carried out under mild conditions using a catalytic amount of a base like triethylamine.
What industries use 2-[1-(Tert-butoxycarbonyl)piperidin-4-yl]propanoic acid (CAS: 815593-60-3)?
2-[1-(Tert-butoxycarbonyl)piperidin-4-yl]propanoic acid is used in the pharmaceutical industry for the synthesis of complex molecules, particularly those containing a piperidine ring. It is also used in the polymer industry for the development of new materials and in sensors for its specific reactivity towards certain functional groups.
What precautions should be taken when handling 2-[1-(Tert-butoxycarbonyl)piperidin-4-yl]propanoic acid (CAS: 815593-60-3)?
When handling 2-[1-(Tert-butoxycarbonyl)piperidin-4-yl]propanoic acid, wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the work is conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling guidelines.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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