![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
{(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide | CAS No. 81522-68-1
{(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide
Basic Information
CAS Number
81522-68-1
Molecular Formula
C33H51O3ψ2
Molecular Weight
582.91 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- 3S-(1Z,3A,5B)-2-[3,5-Bis(tert-butyldimethylsilyloxy)-2-methylenecyclohexylidene]ethyldiphenylphosphine oxide
- tert-butyl({[(1R,3S,5Z)-3-[(tert-butyldimethylsilyl)oxy]-5-[2-(diphenylphosphoroso)ethylidene]-4-methylidenecyclohexyl]oxy})dimethylsilane
- DTXSID00456023
- ((Z)-2-((3S,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethyl)diphenylphosphine oxide
- AC-8891
- AKOS015964462
- MFCD08703326
- {(2Z)-2-[(3S,5R)-3,5-Bis{[tert-butyl(dimethyl)silyl]oxy}-2-methylidenecyclohexylidene]ethyl}(oxo)diphenyl-lambda~5~-phosphane
- Phosphineoxide,[2-[3,5-bis[[(1,1-dimethylethyl)dimethylsily]oxy]-2-methylenecyclohexylidene]ethyl]diphenyl-,[3s-(1z,3a,5b0)]
- Phosphine oxide, [2-[3,5-bis [[(1,1-dimethylethyl) dimethylsily]oxy]-2-methylenecyclohexylidene]ethyl]diphenyl-,[3s-(1z,3a,5b0)]
- ((Z)-2-((3R,5S)-3,5-BIS((TERT-BUTYLDIMETHYLSILYL)OXY)-2-METHYLENECYCLOHEXYLIDENE)ETHYL)DIPHENYLPHOSPHINEOXIDE
- Tert-butyl-[(1R,3S,5Z)-3-[tert-butyl(dimethyl)silyl]oxy-5-(2-diphenylphosphorylethylidene)-4-methylidenecyclohexyl]oxy-dimethylsilane
- 81522-68-1
- CS-M1835
- Phosphine oxide, [(2Z)-2-[(3S,5R)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethyl]diphenyl-
- BCP14765
- CID 11124745
- AS-75150
- SCHEMBL3211756
- [3S-(1Z,3a,5b)]-[2-[3,5-Bis[[(tert-butyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethyl]diphenylphosphineoxide
- [(2Z)-2-[(3S,5R)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethyl]diphenylphosphine Oxide
- [3S-(1Z, 3A,5B)]-[2-{3,5-BIS-{[(1,1-DIMETHYLETHYL)-DIMETHYLS
- [3S-(1Z,3a,5b)]-[2-{3,5-bis-{[(1,1-dimethylethyl)-dimethylsilyl]-oxy}-2-methylenecyclohexylidene}-ethyl]-diphenyl phosphine oxide
- Phosphine Oxide,[2-[3,5-bis [[(1,1-Dimethylethyl) Dimethylsily]oxy]-2-methylenecyclohexylidene]ethyl]diphenyl-,[3S-(1Z,3a,5b0)
- tert-butyl-[(1R,3S,5Z)-3-[tert-butyl(dimethyl)silyl]oxy-5-(2-diphenylphosphorylethylidene)-4-methylidenecyclohexyl]oxy-dimethylsilane
- PHOSPHINE OXIDE, [2-[3,5-BIS [[(1,1-DIMETHYLETHYL) DIMETHYLSILY]OXY]-2-METHYLENECYCLOHEXYLIDENE]ETHYL]DIPHENYL-,[3S-(1Z,3A,5B0)]
MDL Number
MFCD08703326
FAQ
What are the physical and chemical properties of (2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide (CAS: 81522-68-1)?
The compound (2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide has a crystalline form. The molecular weight is approximately 738.58 g/mol. It is poorly soluble in water but soluble in organic solvents like dichloromethane and acetone. Chemically, it is stable under normal conditions but can react with strong bases and acids. The compound is not flammable and has a low reactivity under standard laboratory conditions.
How is (2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide (CAS: 81522-68-1) typically synthesized?
(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide is synthesized using a multistep reaction involving the use of silyl ethers and phosphine oxides. The reaction typically involves the condensation of a silyl ether with a phosphine oxide in the presence of a Lewis acid catalyst. The yield is generally high with good selectivity, and the reaction is typically carried out under anhydrous conditions.
What industries use (2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide (CAS: 81522-68-1)?
(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the polymer industry as a catalyst for the polymerization of various monomers. Additionally, it finds applications in the development of sensors and semiconductors due to its unique chemical properties.
What precautions should be taken when handling (2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide (CAS: 81522-68-1)?
When handling (2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. In the event of a spill, it should be cleaned up using appropriate absorbent materials and the area should be properly decontaminated. Always refer to the Safety Data Sheet (SDS) for the most up-to-date handling and safety information.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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