{(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide(CAS: 81522-68-1)

The compound (2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide has a crystalline form. The molecular weight is approximately 738.58 g/mol. It is poorly soluble in water but soluble in organic solvents like dichloromethane and acetone. Chemically, it is stable under normal conditions but can react with strong bases and acids. The compound is not flammable and has a low reactivity under standard laboratory conditions.

(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide is synthesized using a multistep reaction involving the use of silyl ethers and phosphine oxides. The reaction typically involves the condensation of a silyl ether with a phosphine oxide in the presence of a Lewis acid catalyst. The yield is generally high with good selectivity, and the reaction is typically carried out under anhydrous conditions.

(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the polymer industry as a catalyst for the polymerization of various monomers. Additionally, it finds applications in the development of sensors and semiconductors due to its unique chemical properties.

When handling (2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. In the event of a spill, it should be cleaned up using appropriate absorbent materials and the area should be properly decontaminated. Always refer to the Safety Data Sheet (SDS) for the most up-to-date handling and safety information.