Compound Q&A
How is (2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide (CAS: 81522-68-1) typically synthesized?
Answer
![{(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide](https://static.chemtradehub.com/structs/815/81522-68-1-10ae.webp "{(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide")
(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide is synthesized using a multistep reaction involving the use of silyl ethers and phosphine oxides. The reaction typically involves the condensation of a silyl ether with a phosphine oxide in the presence of a Lewis acid catalyst. The yield is generally high with good selectivity, and the reaction is typically carried out under anhydrous conditions.
About
CAS No
81522-68-1
English Name
{(2Z)-2-[(3S,5R)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-methylenecyclohexylidene]ethyl}(diphenyl)phosphine oxide
Molecular Formula
C33H51O3ψ2
Molecular Weight
582.91 g/mol
SMILES
CC(C)(C)[Si](C)(C)OC1CC(C(=C)C(=CCP(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C1)O[Si](C)(C)C(C)(C)C
InChIKey
MDDUHVRJJAFRAU-YZNNVMRBSA-N
Last Updated: 2025-12-25 13:43
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