(R)-2-Amino-2-methyl-3-hydroxypropanoicacid

Basic Information

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CAS Number

81132-44-7

Molecular Formula

C4H9NO3

Molecular Weight

119.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

286-288 ºC

Boiling Point

222.38°C (rough estimate)

Density

1.3126 (rough estimate)

Refractive Index

1.4183 (estimate)

Specific Rotation

-3.3 º (c=5,6N HCl 25 ºC)

SMILES

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CC(CO)(C(=O)O)N

InChI

InChI=1S/C4H9NO3/c1-4(5,2-6)3(7)8/h6H,2,5H2,1H3,(H,7,8)/t4-/m1/s1

InChIKey

CDUUKBXTEOFITR-SCSAIBSYSA-N

LogP

-1.2192999999999998

Topological Polar Surface Area

83.55000000000001 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

104

Synonyms & References

English

H-2-Me-D-Ser-OH
SCHEMBL161672
H--Me-D-Ser-OH
a-methyl-d-serine
2-Methyl-D-serine
(R)-2-AMINO-2-METHYL-3-HYDROXYPROPANOIC ACID
(2R)-2-ammonio-3-hydroxy-2-methylpropanoate
ALPHA-METHYL-D-SER
(R)-2-methylserine
CDUUKBXTEOFITR-SCSAIBSYSA-N
D-SERINE, 2-METHYL-
AS-38121
DTXSID60331428
(2R)-2-amino-3-hydroxy-2-methylpropionic acid
AB03932
CHEBI:134205
A inverted exclamation mark-Methyl-D-Ser
CS-0136603
?-Methyl-D-serine
AKOS006342337
F15126
MFCD00145210
(R)-2-Amino-2-methyl-3-hydroxypropanoicacid
(-)-(r)-alpha-methylserine
alpha -Methyl-D-serine
BCP10469
ALPHA-METHYL-D-SERINE
(R)-2-AMINO-3-HYDROXY-2-METHYLPROPANOIC ACID
AC-3443
(R)-(-)-2-Amino-3-hydroxy-2-methylpropionic Acid

MDL Number

MFCD00145210

Customs Code

2922509090

FAQ

What are the physical and chemical properties of (R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7)?

(R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7) is a crystalline solid with a molecular weight of approximately 139.16 g/mol. It is slightly soluble in water and has a pKa of about 11.2. This compound is reactive towards nucleophiles and can participate in various chemical reactions.

How is (R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7) typically synthesized?

(R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7) can be synthesized through stereoselective amination of (R)-2-hydroxy-2-methylpropanoic acid. Commonly, this involves using a chiral amination reagent or a biocatalytic approach under mild conditions to achieve high selectivity and yield.

What industries use (R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7)?

(R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7) is primarily used in the pharmaceutical industry as a precursor for the synthesis of chiral compounds. It also finds applications in the development of sensors and as a building block in the polymer industry.

What precautions should be taken when handling (R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7)?

When handling (R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the work area is well-ventilated or use a fume hood. Follow standard safety protocols for handling chemicals, and store the compound in a cool, dry place away from direct sunlight. Always consult the Safety Data Sheet (SDS) for detailed safety information.