(R)-2-Amino-2-methyl-3-hydroxypropanoicacid(CAS: 81132-44-7)

(R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7) is a crystalline solid with a molecular weight of approximately 139.16 g/mol. It is slightly soluble in water and has a pKa of about 11.2. This compound is reactive towards nucleophiles and can participate in various chemical reactions.

(R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7) can be synthesized through stereoselective amination of (R)-2-hydroxy-2-methylpropanoic acid. Commonly, this involves using a chiral amination reagent or a biocatalytic approach under mild conditions to achieve high selectivity and yield.

(R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7) is primarily used in the pharmaceutical industry as a precursor for the synthesis of chiral compounds. It also finds applications in the development of sensors and as a building block in the polymer industry.

When handling (R)-2-Amino-2-methyl-3-hydroxypropanoic acid (CAS: 81132-44-7), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the work area is well-ventilated or use a fume hood. Follow standard safety protocols for handling chemicals, and store the compound in a cool, dry place away from direct sunlight. Always consult the Safety Data Sheet (SDS) for detailed safety information.