7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid

Basic Information

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CAS Number

80353-94-2

Molecular Formula

C9H8N2O2

Molecular Weight

176.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

245-247 ºC

Density

1.35

SMILES

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CC1=CC2=NC(=CN2C=C1)C(=O)O

InChI

InChI=1S/C9H8N2O2/c1-6-2-3-11-5-7(9(12)13)10-8(11)4-6/h2-5H,1H3,(H,12,13)

InChIKey

GWOWWQVYWZHBRI-UHFFFAOYSA-N

LogP

1.34092

Topological Polar Surface Area

54.60000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

220

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

J-519317
7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid, AldrichCPR
IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID, 7-METHYL-
MFCD13194051
GWOWWQVYWZHBRI-UHFFFAOYSA-N
7-methylimidazo[1,2-a]pyridine-2-carboxylicacid
FT-0745651
A853498
MFCD03425067
Z89283367
DTXSID00360070
EN300-13230
A839897
7-methylimidazo[1,2-a]pyridine-2-carboxylic acid
7-methyl-2-imidazo[1,2-a]pyridinecarboxylic acid
SCHEMBL1759007
F9995-2683
80353-94-2
7-Methylimidazo[1 pound not2-a]pyridine-2-carboxylic acid
7-Methyl-imidazo[1,2-a]pyridine-2-carboxylic acid
AM20070241
HMS1367D12
Bionet2_001134
7W-0867
CS-0081074
AB14570
AKOS000300606
7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid
Imidazo[1,2-a]pyridine-2-carboxylicacid, 7-methyl-
7-methylimidazo[1,2-a]pyridine-2-carboxylic acid(SALTDATA: 0.5H2O)
methylimidazoapyridinecarboxylicacid

MDL Number

MFCD03425067

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2)?

7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2) is a crystalline solid with a molecular weight of approximately 213.24 g/mol. It has a solubility of about 0.04 g/100 mL in water. The compound is moderately reactive, particularly in acidic conditions. It shows good stability in neutral to slightly basic environments.

How is 7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2) typically synthesized?

7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2) can be synthesized through a multi-step process involving the condensation of 7-methylimidazol with pyridine. A common method involves using acetic anhydride as a coupling agent and a strong base like sodium hydride to facilitate the reaction, leading to a selective yield of about 85%.

What industries use 7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2)?

7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2) is primarily used in the pharmaceutical industry for drug development. It also has applications in the polymer industry as a stabilizer and in the field of sensors for its unique chemical reactivity. Additionally, it is explored in semiconductor technology for its electronic properties.

What precautions should be taken when handling 7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2)?

When handling 7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety instructions.