7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid(CAS: 80353-94-2)

7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2) is a crystalline solid with a molecular weight of approximately 213.24 g/mol. It has a solubility of about 0.04 g/100 mL in water. The compound is moderately reactive, particularly in acidic conditions. It shows good stability in neutral to slightly basic environments.

7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2) can be synthesized through a multi-step process involving the condensation of 7-methylimidazol with pyridine. A common method involves using acetic anhydride as a coupling agent and a strong base like sodium hydride to facilitate the reaction, leading to a selective yield of about 85%.

7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2) is primarily used in the pharmaceutical industry for drug development. It also has applications in the polymer industry as a stabilizer and in the field of sensors for its unique chemical reactivity. Additionally, it is explored in semiconductor technology for its electronic properties.

When handling 7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 80353-94-2), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety instructions.