4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (1:1) | CAS No. 79617-89-3
4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (1:1)
Basic Information
CAS Number
79617-89-3
Molecular Formula
C17H18Cl3N
Molecular Weight
342.7 g/mol
AD
Basic Physical Properties
Melting Point
275-277 ºC
Boiling Point
443.8°C at 760 mmHg
Flash Point
222.2°C
Synonyms & References
English
- 329009-20-3
- 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-
- 79617-89-3
- FT-0641726
- 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride
- ( inverted exclamation markA)-Sertraline hydrochloride,1R,4R)-rel-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride
- CHEMBL1415862
- NCGC00095151-01
- F0001-2405
- AB07662
- 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride
- 1-Naphthalenamine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, hydrochloride,(1R,4R)-rel-
- SY032692
- 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenaminehydrochloride
- NCGC00095151-02
- FT-0674567
- CS-0301414
- FT-0700687
- EN300-296115
- 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydron-methyl-1-naphthalenamine hydrochloride
- AKOS015900976
- FT-0768987
- SCHEMBL3695433
- FT-0674566
- (1S,4S)-4-(3,4-Dichlorophenyl)-1-(methylamino)-1,2,3,4-tetrahydronaphthalene Hydrochloride
- A839724
- 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride
- 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-aminehydrochloride
- Sertraline basis
- rac-cis-Sertraline Hydrochloride
- cis-N-Methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride
MDL Number
MFCD08703316
FAQ
What are the physical and chemical properties of 4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (CAS: 79617-89-3)?
4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride is a solid with a crystalline form. Its molecular weight is approximately 353.96 g/mol. The compound has low water solubility but good solubility in organic solvents like methanol and acetonitrile. It is an amphoteric compound, meaning it can act as both an acid and a base, and it is highly reactive towards nucleophiles. It decomposes above 150°C.
How is 4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (CAS: 79617-89-3) typically synthesized?
4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride is synthesized from 3,4-dichloroaniline and 1-naphthylmagnesium bromide in the presence of a catalytic amount of magnesium chloride. The reaction is typically carried out in tetrahydrofuran (THF) or another suitable organic solvent. The product is then treated with hydrochloric acid to form the hydrochloride salt.
What industries use 4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (CAS: 79617-89-3)?
4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride is primarily used in the pharmaceutical industry for the synthesis of various drug intermediates. It is also utilized in the polymer industry as a precursor for functionalized polymers and in the sensor industry for developing chemical sensors. Additionally, it has applications in the semiconductor industry as a dopant for organic semiconductors.
What precautions should be taken when handling 4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (CAS: 79617-89-3)?
When handling 4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a laboratory coat. It should be used in a well-ventilated fume hood to minimize exposure to vapors. In case of spill, avoid direct contact and clean up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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