Compound Q&A

How is 4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (CAS: 79617-89-3) typically synthesized?

Answer

4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (1:1)
4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride is synthesized from 3,4-dichloroaniline and 1-naphthylmagnesium bromide in the presence of a catalytic amount of magnesium chloride. The reaction is typically carried out in tetrahydrofuran (THF) or another suitable organic solvent. The product is then treated with hydrochloric acid to form the hydrochloride salt.

About

CAS No 79617-89-3
English Name 4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (1:1)
Molecular Formula C17H18Cl3N
Molecular Weight 342.7 g/mol
SMILES CNC1CCC(C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl
InChIKey BLFQGGGGFNSJKA-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14

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