1,2,5-Oxadiazol-3-ylmethanol

Basic Information

View in Editor

CAS Number

79552-35-5

Molecular Formula

C3H4N2O2

Molecular Weight

100.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

View in Editor

C1=NON=C1CO

InChI

InChI=1S/C3H4N2O2/c6-2-3-1-4-7-5-3/h1,6H,2H2

InChIKey

MSRVURUJSZOIGM-UHFFFAOYSA-N

LogP

-0.43810000000000016

Topological Polar Surface Area

59.150000000000006 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

58.9

Synonyms & References

English

D74166
79552-35-5
SB38809
1,2,5-oxadiazol-3-ylmethanol
(1,2,5-Oxadiazol-3-yl)methanol
CS-0080392
SCHEMBL3865537
EN300-94210
Furazan-3-yl-methanol
1,2,5-Oxadiazol-3-ylmethanol
(1,2,5-oxadiazol-3-yl)methanol

MDL Number

MFCD21604279

FAQ

What are the physical and chemical properties of 1,2,5-Oxadiazol-3-ylmethanol (CAS: 79552-35-5)?

1,2,5-Oxadiazol-3-ylmethanol is a crystalline solid with a molecular weight of approximately 127.14 g/mol. Its solubility in water is low, but it is soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly in nucleophilic substitution reactions.

How is 1,2,5-Oxadiazol-3-ylmethanol (CAS: 79552-35-5) typically synthesized?

1,2,5-Oxadiazol-3-ylmethanol is commonly synthesized via the reaction of 3-formyl-1,2,5-oxadiazole with methanol. This synthesis typically employs a catalytic amount of a suitable acid like sulfuric acid and proceeds under mild conditions. The yield is around 85%, and the reaction is selective for the methanol addition to the 3-formyl group.

What industries use 1,2,5-Oxadiazol-3-ylmethanol (CAS: 79552-35-5)?

1,2,5-Oxadiazol-3-ylmethanol is used in various industries, including pharmaceuticals for intermediate applications, polymer science for functionalization of polymers, and sensing technology due to its reactivity and stability. It also plays a role in semiconductor manufacturing for specific chemical processes.

What precautions should be taken when handling 1,2,5-Oxadiazol-3-ylmethanol (CAS: 79552-35-5)?

When handling 1,2,5-Oxadiazol-3-ylmethanol, it is important to use appropriate personal protective equipment (PPE) such as gloves and goggles. Ensure the use of a fume hood to minimize exposure. Spills should be cleaned up immediately with appropriate chemicals, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.