Compound Q&A

How is 1,2,5-Oxadiazol-3-ylmethanol (CAS: 79552-35-5) typically synthesized?

Answer

1,2,5-Oxadiazol-3-ylmethanol
1,2,5-Oxadiazol-3-ylmethanol is commonly synthesized via the reaction of 3-formyl-1,2,5-oxadiazole with methanol. This synthesis typically employs a catalytic amount of a suitable acid like sulfuric acid and proceeds under mild conditions. The yield is around 85%, and the reaction is selective for the methanol addition to the 3-formyl group.

About

CAS No 79552-35-5
English Name 1,2,5-Oxadiazol-3-ylmethanol
Molecular Formula C3H4N2O2
Molecular Weight 100.08 g/mol
SMILES C1=NON=C1CO
InChIKey MSRVURUJSZOIGM-UHFFFAOYSA-N
Last Updated: 2026-04-01 19:31

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