(6R,7R)-7-({(2-Amino-1,3-thiazol-4-yl)[(carboxymethoxy)imino]acetyl}amino)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Basic Information

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CAS Number

79350-37-1

Molecular Formula

C16H15N5O7S2

Molecular Weight

453.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Melting Point

218-225 ºC

Water Solubility

55.11 mg/L

SMILES

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C=CC1=C(N2C(C(C2=O)NC(=O)C(=NOCC(=O)O)C3=CSC(=N3)N)SC1)C(=O)O

InChI

InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/t10-,14-/m1/s1

InChIKey

OKBVVJOGVLARMR-QMTHXVAHSA-N

LogP

-0.5447999999999993

Topological Polar Surface Area

184.51 Å²

Hydrogen Bond Donor/Acceptor

5 / 12

Complexity

861

Safety Information

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Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Synonyms & References

English

Anhydrous cefixime
Cephoral
SCHEMBL24945
Denvar
(E)-CEFIXIME (CEFIXIME EP IMPURITY D)
Oraken
(6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7(sup 2)-(Z)-(O-(carboxymethyl)oxime) trihydrate
(6R,7R)-7-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Tricef
UNII-XZ7BG04GJX
5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-(((2-amino-4-thiazolyl)((carboxymethoxy)imino)acetyl)amino)3-ethenyl-8-oxo-, trihydrate, (6R-(6alpha,7beta(Z)))-
CEFIXIME [MI]
Cefixime (INN)
HMS3713M06
BRD-K71059170-001-02-5
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)((carboxymethoxy)imino)acetyl)amino)-3-ethenyl-8-oxo-, trihydrate, (6R-(6alpha,7beta(Z)))-
Cefixima
NCGC00179521-01
CEFIXIME [WHO-DD]
(6R,7R)-7-((2-(2-AMINO-1,3-THIAZOL-4-YL)-2-(CARBOXYMETHOXYIMINO)ACETYL)AMINO)-3-ETHENYL-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID
(6R,7R)-7-(((2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-((carboxymethoxy)imino)acetyl)amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
XZ7BG04GJX
Cefixime, Antibiotic for Culture Media Use Only
SR-01000760706-4
HMS2234J21
CHEBI:472657
AKOS015854940
Cefiximum
(-)-Cefixim
CL-284635
CEFIXIME (EP MONOGRAPH)

MDL Number

MFCD00865020

Customs Code

2941905990

FAQ

What is (6R,7R)-7-({(2-Amino-1,3-thiazol-4-yl)[(carboxymethoxy)imino]acetyl}amino)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (CAS: 79350-37-1)?

This compound, with the CAS number 79350-37-1, is a complex organic molecule containing a thiazole ring and multiple functional groups such as amino, carboxylic acid, and vinyl. It is characterized by its stereochemistry (6R,7R) and exhibits structural features typical of azabicyclic compounds. Its molecular formula is C15H17N5O6S2, and it is known for its potential biological activity due to the presence of heterocyclic and amide functionalities.

What are the main uses of (6R,7R)-7-({(2-Amino-1,3-thiazol-4-yl)[(carboxymethoxy)imino]acetyl}amino)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (CAS: 79350-37-1)?

This compound is primarily used in pharmaceutical research as a potential inhibitor of specific enzymes, particularly those involved in metabolic pathways. Its unique structure makes it a candidate for drug development targeting diseases such as cancer or infectious disorders. Additionally, it may find applications in chemical synthesis and as a research reagent for studying molecular interactions and biological mechanisms.

Is (6R,7R)-7-({(2-Amino-1,3-thiazol-4-yl)[(carboxymethoxy)imino]acetyl}amino)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (CAS: 79350-37-1) safe?

Safety data for this compound is limited, but as with many complex organic chemicals, it should be handled with care. Precautions include wearing personal protective equipment (PPE) such as gloves and goggles, and avoiding inhalation or skin contact. It is advisable to follow standard chemical safety protocols and consult safety data sheets (SDS) for detailed handling and exposure guidelines.

How should (6R,7R)-7-({(2-Amino-1,3-thiazol-4-yl)[(carboxymethoxy)imino]acetyl}amino)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (CAS: 79350-37-1) be stored?

This compound should be stored in a cool, dry, and dark place, preferably at 2-8°C. It is important to maintain low humidity levels and protect it from light exposure to preserve its stability. It should be kept in a sealed, airtight container made of inert material such as glass or polyethylene to prevent contamination and degradation.