5-hydroxy-4-propyl-2,5-dihydrofuran-2-one

Basic Information

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CAS Number

78920-10-2

Molecular Formula

C7H10O3

Molecular Weight

142.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

325.76°C at 760 mmHg

Density

1.198

Flash Point

152.212°C

Refractive Index

1.508

SMILES

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CCCC1=CC(=O)OC1O

InChI

InChI=1S/C7H10O3/c1-2-3-5-4-6(8)10-7(5)9/h4,7,9H,2-3H2,1H3

InChIKey

KQMCGGGTJKNIMC-UHFFFAOYSA-N

LogP

0.5881000000000001

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

172

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

EN300-7381318
2-hydroxy-3-propyl-2H-furan-5-one
78920-10-2
5-hydroxy-4-propyl-5H-furan-2-one
DTXSID00511823
MFCD11977490
AMY16474
SY106260
A9886
CALCIUMFERROCYANIDE
SB60867
SCHEMBL364738
5-hydroxy-4-n-propyl-5H-furan-2-one
AC-30120
AKOS015899559
2(5H)-Furanone, 5-hydroxy-4-propyl-
CS-B0865
5-hydroxy-4-propylfuran-2(5H)-one
5-hydroxy-4-n-propylfuran-2-one
CC2DW9CB83
SC5106
KQMCGGGTJKNIMC-UHFFFAOYSA-N
5-hydroxy-4-propyl-2,5-dihydrofuran-2-one
FT-0769422
5-HYDROXY-4-PROPYL-2(5H)-FURANONE
5-Hydroxy-4-propylfuran-2(5H)-one
5-hydroxy-4-n-propyl-furan-2-one

MDL Number

MFCD11977490

Customs Code

2932209090

FAQ

What are the physical and chemical properties of 5-hydroxy-4-propyl-2,5-dihydrofuran-2-one (CAS: 78920-10-2)?

5-hydroxy-4-propyl-2,5-dihydrofuran-2-one is a colorless or white crystalline solid with a molecular weight of approximately 132.15 g/mol. It has a moderate solubility in common organic solvents such as ethanol and methanol. The compound is known for its reactivity, particularly towards nucleophiles and electrophiles. It is stable under normal conditions but should be stored in a sealed container at room temperature to avoid degradation.

How is 5-hydroxy-4-propyl-2,5-dihydrofuran-2-one (CAS: 78920-10-2) typically synthesized?

5-hydroxy-4-propyl-2,5-dihydrofuran-2-one can be synthesized via the condensation of propionaldehyde and 2-hydroxy-4-oxo-1,3-dioxol-5-one. The reaction typically uses a mild base such as potassium carbonate in an aqueous-organic solvent mixture. The yield is generally good, and the selectivity is high, making it a reliable method for producing this compound.

What industries use 5-hydroxy-4-propyl-2,5-dihydrofuran-2-one (CAS: 78920-10-2)?

5-hydroxy-4-propyl-2,5-dihydrofuran-2-one is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the polymer industry for the production of certain polymers with specific properties. Additionally, it finds applications in the sensor technology for detecting specific chemicals and in semiconductor manufacturing for specific etching processes.

What precautions should be taken when handling 5-hydroxy-4-propyl-2,5-dihydrofuran-2-one (CAS: 78920-10-2)?

When handling 5-hydroxy-4-propyl-2,5-dihydrofuran-2-one, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. In case of a spill, immediately clean it up using appropriate absorbents and dispose of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.