1,4,8-Trimethyl-9H-carbazole

Basic Information

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CAS Number

78787-83-4

Molecular Formula

C15H15N

Molecular Weight

209.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

154-156 ºC

Density

1.132±0.06 g/cm3 (20 ºC 760 Torr),

Solubility

Insuluble (1.4E-3 g/L) (25 ºC),

SMILES

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CC1=C2C(=CC=C1)C3=C(C=CC(=C3N2)C)C

InChI

InChI=1S/C15H15N/c1-9-7-8-11(3)15-13(9)12-6-4-5-10(2)14(12)16-15/h4-8,16H,1-3H3

InChIKey

DKMJSUBUAMUZAJ-UHFFFAOYSA-N

LogP

4.246360000000003

Topological Polar Surface Area

15.79 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

262

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1,4,8-Trimethyl-9H-carbazole
78787-83-4
9H-Carbazole, 1,4,8-trimethyl-
AKOS015993035
1,4,8-Trimethyl-9H-carbazole;Carbazole, 1,4,8-trimethyl-
SCHEMBL15201047
DKMJSUBUAMUZAJ-UHFFFAOYSA-N
1,4,8-Trimethyl-9H-carbazole #
5Z-0826
A864962
Carbazole, 1,4,8-trimethyl-
D83147
BCP31719
1,4,8-Trimethylcarbazole
1,5,8-Trimethylcarbazole
1,4,8-trimethyl-carbazole

MDL Number

MFCD18450124

FAQ

What are the physical and chemical properties of 1,4,8-Trimethyl-9H-carbazole (CAS: 78787-83-4)?

1,4,8-Trimethyl-9H-carbazole is a solid at room temperature with a crystalline form. Its molecular weight is approximately 204.25 g/mol. It has low water solubility but good solubility in organic solvents such as benzene and chloroform. Chemically, it is moderately reactive towards nucleophiles, making it useful in various synthetic transformations.

How is 1,4,8-Trimethyl-9H-carbazole (CAS: 78787-83-4) typically synthesized?

1,4,8-Trimethyl-9H-carbazole is commonly synthesized via the multistep coupling of benzene derivatives with methyl iodide in the presence of a Lewis acid catalyst, such as aluminum chloride. The process typically yields a high percentage of the desired product with good selectivity.

What industries use 1,4,8-Trimethyl-9H-carbazole (CAS: 78787-83-4)?

1,4,8-Trimethyl-9H-carbazole is used in the pharmaceutical industry for the synthesis of certain alkaloids, in polymer production for its UV-absorbing properties, in the semiconductor industry for doping materials, and in the manufacturing of sensors for detecting specific chemicals.

What precautions should be taken when handling 1,4,8-Trimethyl-9H-carbazole (CAS: 78787-83-4)?

When handling 1,4,8-Trimethyl-9H-carbazole, use appropriate PPE such as gloves and safety goggles. Work in a fume hood to avoid inhalation. Keep away from heat and oxidizers. In case of spill, avoid direct contact and clean up using appropriate absorbent material. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.