1,4,8-Trimethyl-9H-carbazole(CAS: 78787-83-4)

1,4,8-Trimethyl-9H-carbazole is a solid at room temperature with a crystalline form. Its molecular weight is approximately 204.25 g/mol. It has low water solubility but good solubility in organic solvents such as benzene and chloroform. Chemically, it is moderately reactive towards nucleophiles, making it useful in various synthetic transformations.

1,4,8-Trimethyl-9H-carbazole is commonly synthesized via the multistep coupling of benzene derivatives with methyl iodide in the presence of a Lewis acid catalyst, such as aluminum chloride. The process typically yields a high percentage of the desired product with good selectivity.

1,4,8-Trimethyl-9H-carbazole is used in the pharmaceutical industry for the synthesis of certain alkaloids, in polymer production for its UV-absorbing properties, in the semiconductor industry for doping materials, and in the manufacturing of sensors for detecting specific chemicals.

When handling 1,4,8-Trimethyl-9H-carbazole, use appropriate PPE such as gloves and safety goggles. Work in a fume hood to avoid inhalation. Keep away from heat and oxidizers. In case of spill, avoid direct contact and clean up using appropriate absorbent material. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.