3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide | CAS No. 785-74-0
3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide
Basic Information
CAS Number
785-74-0
Molecular Formula
C11H10F3NO2
Molecular Weight
245.2 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- MFCD00201876
- CBDivE_003057
- 3'-trifluoromethylacetoacetanilide
- Z56867225
- 3-oxo-N-[3-(trifluoromethyl)phenyl]butanamide
- DTXSID60353524
- 3-Oxo-N-(3-(trifluoromethyl)phenyl)butanamide
- 785-74-0
- CS-0218576
- SR-01000389271
- EU-0066748
- SCHEMBL9429509
- SR-01000389271-1
- 10D-067
- 3-Oxo-N-(3-trifluoromethyl-phenyl)-butyramide
- AKOS000115168
- EN300-01414
- 3'-trifluoromethyl acetoacetanilide
- Butanamide,3-oxo-N-[3-(trifluoromethyl)phenyl]-
- 3-OXO-N-(3-TRIFLUOROMETHYL-PHENYL)-BUTYRAMIDE
MDL Number
MFCD00201876
FAQ
What are the physical and chemical properties of 3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide (CAS: 785-74-0)?
3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide (CAS: 785-74-0) is a colorless or white crystalline solid with a molecular weight of approximately 295.13 g/mol. It has a high melting point and is poorly soluble in water but soluble in organic solvents like methanol and acetonitrile. The compound is known for its reactivity, particularly its ability to undergo nucleophilic substitution and condensation reactions.
How is 3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide (CAS: 785-74-0) typically synthesized?
3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide (CAS: 785-74-0) can be synthesized via an amide coupling reaction between 3-(trifluoromethyl)benzoyl chloride and 3-butanone in the presence of a suitable base like triethylamine. This method provides good yield and selectivity, and the reaction is typically carried out in a non-polar organic solvent like dichloromethane.
What industries use 3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide (CAS: 785-74-0)?
3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide (CAS: 785-74-0) is primarily used in the pharmaceutical industry due to its structural similarity to certain bioactive compounds. It may also find applications in polymer chemistry, where its unique electronic properties could be exploited for developing new materials. Additionally, it could be utilized in the development of sensors and semiconductors.
What precautions should be taken when handling 3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide (CAS: 785-74-0)?
When handling 3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide (CAS: 785-74-0), it is crucial to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be immediately cleaned up using appropriate absorbent materials, and the area should be thoroughly rinsed. Always refer to the safety data sheet (SDS) for comprehensive safety information and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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