Compound Q&A
How is 3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide (CAS: 785-74-0) typically synthesized?
Answer
![3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide](https://static.chemtradehub.com/structs/785/785-74-0-49b0.webp "3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide")
3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide (CAS: 785-74-0) can be synthesized via an amide coupling reaction between 3-(trifluoromethyl)benzoyl chloride and 3-butanone in the presence of a suitable base like triethylamine. This method provides good yield and selectivity, and the reaction is typically carried out in a non-polar organic solvent like dichloromethane.
About
CAS No
785-74-0
English Name
3-Oxo-N-[3-(trifluoromethyl)phenyl]butanamide
Molecular Formula
C11H10F3NO2
Molecular Weight
245.2 g/mol
SMILES
CC(=O)CC(=O)NC1=CC=CC(=C1)C(F)(F)F
InChIKey
YOTPJLYOOXQHKX-UHFFFAOYSA-N
Last Updated: 2026-03-23 04:12
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