3-(2-Naphthyloxy)azetidine

Basic Information

View in Editor

CAS Number

784123-27-9

Molecular Formula

C13H13NO

Molecular Weight

199.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

View in Editor

C1C(CN1)OC2=CC3=CC=CC=C3C=C2

InChI

InChI=1S/C13H13NO/c1-2-4-11-7-12(6-5-10(11)3-1)15-13-8-14-9-13/h1-7,13-14H,8-9H2

InChIKey

ZQXUEIDHHHQAEN-UHFFFAOYSA-N

LogP

2.1903999999999995

Topological Polar Surface Area

21.259999999999998 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

215

Safety Information

View Safety Information

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

SB50988
784123-27-9
FT-0681354
EN300-1843415
3-naphthalen-2-yloxyazetidine
CS-0270499
3-(naphthalen-2-yloxy)azetidine
AKOS012080622
A1-35639
DTXSID00625712
3-(2-NAPHTHYLOXY)AZETIDINE
SCHEMBL23842763
3-[(Naphthalen-2-yl)oxy]azetidine
3-(2-Naphthyloxy)azetidine

MDL Number

MFCD13559974

FAQ

What are the physical and chemical properties of 3-(2-Naphthyloxy)azetidine (CAS: 784123-27-9)?

3-(2-Naphthyloxy)azetidine is a crystalline compound with a molecular weight of approximately 212.26 g/mol. It has a high solubility in organic solvents like methanol and ethanol but is poorly soluble in water. The compound is moderately reactive, particularly towards nucleophilic substitution reactions. It exhibits good stability under normal storage conditions but requires protection from moisture and light.

How is 3-(2-Naphthyloxy)azetidine (CAS: 784123-27-9) typically synthesized?

3-(2-Naphthyloxy)azetidine can be synthesized via a multistep process involving the coupling of a naphthol derivative with an azetidinone. Common catalysts include Lewis acids like aluminum chloride. The reaction is typically carried out in anhydrous organic solvents at room temperature, yielding a high purify product with good selectivity and a yield of up to 85%.

What industries use 3-(2-Naphthyloxy)azetidine (CAS: 784123-27-9)?

3-(2-Naphthyloxy)azetidine is primarily used in the pharmaceutical industry for the synthesis of bioactive compounds. It also has applications in the polymer industry, where it can be used as a monomer. Additionally, it is explored for its use in sensor technology and semiconductor manufacturing due to its unique chemical properties.

What precautions should be taken when handling 3-(2-Naphthyloxy)azetidine (CAS: 784123-27-9)?

When handling 3-(2-Naphthyloxy)azetidine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be immediately cleaned up using appropriate absorbents, and the area should be flushed with water. Always consult the Safety Data Sheet (SDS) for detailed guidance on safe handling and disposal.