L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl- | CAS No. 78183-34-3

L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl-

Basic Information

CAS Number

78183-34-3

Molecular Formula

C12H24B2O4

Molecular Weight

253.9 g/mol

AD

Basic Physical Properties

Melting Point

137-140 °C

Density

1.428±0.06 g/cm3 (20 ºC 760 Torr),

B1(OC(C(O1)(C)C)(C)C)B2OC(C(O2)(C)C)(C)C

InChI

InChI=1S/C12H24B2O4/c1-9(2)10(3,4)16-13(15-9)14-17-11(5,6)12(7,8)18-14/h1-8H3

InChIKey

IPWKHHSGDUIRAH-UHFFFAOYSA-N

LogP

2.2492

Topological Polar Surface Area

36.92 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

286

Synonyms & References

English

  • 4,4,5,5,4',4',5',5'-Octamethyl-2,2'-bi-1,3,2-dioxaborolane
  • Bispinacolate diboron
  • 4,4,5,5,4',4',5',5'-Octamethyl-[2,2']-bi[[1,3,2]dioxaborolanyl]
  • EC 615-925-0
  • 73183-34-3
  • UNII-I906W26P4U
  • bis(pinacolato) diborane
  • bis-(pinacolato)diboron
  • 4,4,4', 4',5,5,5',5'-octamethyl-2,2'-bi(1,3,2-dioxaborolane)
  • 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • bis(pinacol-ato)diboron
  • bis-pinacolate diboron
  • bis(pinacolate)diborane(4)
  • 4,4,5,5,4',4',5',5'-octamethyl-[2,2]bi[[1,3,2]dioxaborolanyl]
  • 4,4,5,5,4',4',5',5'-octamethyl-[2,2']bi[[1,3,2] dioxaborolanyl]
  • 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bi(1,3,2- dioxaborolane)
  • Bis(pinacolato)diborane [MI]
  • 4,4,5,5,4',4',5',5'-Octamethyl-2,2'-bi(1,3,2)dioxaborolane
  • 4,4,5,5-tetramethyl-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolan
  • 4,4,4',4',5,5,5',5'-Octamethyl[2,2'-bi-1,3,2-dioxaborolane]
  • 4,4,5,5,4',4',5',5'-octamethyl-[2,2']bi[1,3,2]dioxaborolanyl
  • Pinacol diborane
  • 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bi-(1,3,2-dioxaborolane)
  • 4,4,5,5,-tetramethyl-2-(4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane
  • AS-2373
  • AKOS005259663
  • EN300-57239
  • 4,4,4',4',5,5,5',5'-Octamethyl-2,2'-bi-1,3,2-dioxaborolane
  • bis (pinacolato)diboron
  • 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bis(1,3,2-dioxa-borolane)
  • 4,4,5,5-tetramethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxa-borolane

MDL Number

MFCD00799570

FAQ

What are the physical and chemical properties of L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl (CAS: 78183-34-3)?

L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl (CAS: 78183-34-3) is a crystalline compound with a high molecular weight. It is slightly soluble in water and has low solubility in common organic solvents. The compound is known for its chemical reactivity, particularly in peptide bond formation and enzymatic reactions.

How is L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl (CAS: 78183-34-3) typically synthesized?

L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl (CAS: 78183-34-3) is synthesized via solid-phase peptide synthesis (SPPS). Commonly, Fmoc chemistry is used as the protecting group, and various coupling agents like N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) and N-hydroxysuccinimide (NHS) are employed. The synthesis typically yields a high-purity product with a high degree of sequence fidelity.

What industries use L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl (CAS: 78183-34-3)?

L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl (CAS: 78183-34-3) is predominantly used in the pharmaceutical and biotechnology industries for the development of peptide-based drugs and therapeutic agents. It is also utilized in the polymer industry for the synthesis of biodegradable polymers and in the semiconductor industry for the fabrication of peptide-based sensors.

What precautions should be taken when handling L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl (CAS: 78183-34-3)?

When handling L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl (CAS: 78183-34-3), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation exposure. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.

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