Compound Q&A

How is L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl (CAS: 78183-34-3) typically synthesized?

Answer

L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl-
L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl (CAS: 78183-34-3) is synthesized via solid-phase peptide synthesis (SPPS). Commonly, Fmoc chemistry is used as the protecting group, and various coupling agents like N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) and N-hydroxysuccinimide (NHS) are employed. The synthesis typically yields a high-purity product with a high degree of sequence fidelity.

About

CAS No 78183-34-3
English Name L-Phenylalanine,L-threonyl-L-histidyl-L-threonyl-L-asparaginyl-L-isoleucyl-L-seryl-L-a-glutamyl-L-seryl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-threonyl-
Molecular Formula C12H24B2O4
Molecular Weight 253.9 g/mol
SMILES B1(OC(C(O1)(C)C)(C)C)B2OC(C(O2)(C)C)(C)C
InChIKey IPWKHHSGDUIRAH-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15

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