(1R)-1-Cyclobutylethanamine

Basic Information

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CAS Number

778575-09-0

Molecular Formula

C6H13N

Molecular Weight

99.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

SMILES

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CC(C1CCC1)N

InChI

InChI=1S/C6H13N/c1-5(7)6-3-2-4-6/h5-6H,2-4,7H2,1H3/t5-/m1/s1

InChIKey

GDGHPMLCHFTAIY-RXMQYKEDSA-N

LogP

1.1337000000000002

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

57.2

Synonyms & References

English

AKOS006367377
(1R)-1-CYCLOBUTYLETHANAMINE
(r)-1-cyclobutyl-ethylamine
(R)-1-cyclobutylethan-1-amine
EN300-179430
778575-09-0
(1R)-1-cyclobutylethan-1-amine
(R)-1-cyclobutylethanaMine
AM807006
CS-0091441
GDGHPMLCHFTAIY-RXMQYKEDSA-N
(R)-1-cyclobutylethylamine
(R)-1-Cyclobutylethanamine
(1R)-1-cyclobutylethanamine

MDL Number

MFCD18690067

FAQ

What are the physical and chemical properties of (1R)-1-Cyclobutylethanamine (CAS: 778575-09-0)?

(1R)-1-Cyclobutylethanamine is a colorless liquid with a molecular weight of approximately 88.13 g/mol. It has a pKa of about 10.0. The compound is soluble in ethanol, methanol, and dimethylformamide. It is less soluble in water. It reacts readily with strong acids and bases, and has limited reactivity under normal conditions.

How is (1R)-1-Cyclobutylethanamine (CAS: 778575-09-0) typically synthesized?

(1R)-1-Cyclobutylethanamine is typically synthesized via the reaction of cyclobutylamine with (R)-2-bromopropanoic acid under basic conditions. The synthesis involves aminolysis and can be optimized with the use of a base catalyst such as potassium carbonate. The yield is generally around 75-80%, and the product can be purified by distillation.

What industries use (1R)-1-Cyclobutylethanamine (CAS: 778575-09-0)?

(1R)-1-Cyclobutylethanamine finds applications in the pharmaceutical industry, particularly as a precursor in the synthesis of certain drugs. It is also used in the formulation of some polymers and as a reagent in organic synthesis. Additionally, it may have uses in the production of sensors and in semiconductor manufacturing as a dopant material.

What precautions should be taken when handling (1R)-1-Cyclobutylethanamine (CAS: 778575-09-0)?

When handling (1R)-1-Cyclobutylethanamine, wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation of fumes. Store the compound in a cool, dry place away from direct sunlight and heat sources. In the event of a spill, contain the spill using an appropriate absorbent material and dispose of it according to local hazardous waste regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.