Compound Q&A
How is (1R)-1-Cyclobutylethanamine (CAS: 778575-09-0) typically synthesized?
Answer
(1R)-1-Cyclobutylethanamine is typically synthesized via the reaction of cyclobutylamine with (R)-2-bromopropanoic acid under basic conditions. The synthesis involves aminolysis and can be optimized with the use of a base catalyst such as potassium carbonate. The yield is generally around 75-80%, and the product can be purified by distillation.
About
CAS No
778575-09-0
English Name
(1R)-1-Cyclobutylethanamine
Molecular Formula
C6H13N
Molecular Weight
99.18 g/mol
SMILES
CC(C1CCC1)N
InChIKey
GDGHPMLCHFTAIY-RXMQYKEDSA-N
Last Updated: 2026-03-20 02:47
