5-Bromo-2,3'-bipyridine

Basic Information

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CAS Number

774-53-8

Molecular Formula

C10H7BrN2

Molecular Weight

235.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

103-104 ºC

Boiling Point

332.4°C at 760 mmHg

Density

1.493±0.06 g/cm3 (20 ºC 760 Torr),

Flash Point

154.8°C

Refractive Index

1.612

SMILES

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C1=CC(=CN=C1)C2=NC=C(C=C2)Br

InChI

InChI=1S/C10H7BrN2/c11-9-3-4-10(13-7-9)8-2-1-5-12-6-8/h1-7H

InChIKey

ILJRIAPZWHYPMK-UHFFFAOYSA-N

LogP

2.9061000000000003

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

163

Synonyms & References

English

5-Bromo-[2,3']bipyridinyl
5-BROMO-[2,3']-BIPYRIDINE
ILJRIAPZWHYPMK-UHFFFAOYSA-N
BS-2101
CS-0319439
774-53-8
AKOS015941976
SCHEMBL999177
DTXSID10464417
MFCD09037420
2,3'-Bipyridine, 5-bromo-
5-BROMO-2,3'-BIPYRIDINE
5-bromo-2-pyridin-3-ylpyridine
5-Bromo-2,3'-bipyridine
2-(3-pyridyl)-5-bromopyridine
2,3'-Bipyridine,5-bromo
5-BROMO-[2,3']BIPYRIDINE
5-bromo-2-(3-pyridyl)pyridine
3-Bromo-6-(3-pyridyl)pyridine

MDL Number

MFCD09037420

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Bromo-2,3'-bipyridine (CAS: 774-53-8)?

5-Bromo-2,3'-bipyridine (CAS: 774-53-8) is a crystalline solid with a molecular weight of 256.02 g/mol. It is poorly soluble in water but soluble in organic solvents such as ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophiles. It exhibits strong coordination chemistry and is often used in spectroscopic studies.

How is 5-Bromo-2,3'-bipyridine (CAS: 774-53-8) typically synthesized?

5-Bromo-2,3'-bipyridine (CAS: 774-53-8) is typically synthesized by the bromination of 2,3'-bipyridine. Common methods include the use of N-bromosuccinimide (NBS) and peracetic acid as brominating agents. The reaction is carried out in an inert solvent such as methylene chloride or dichloromethane under anhydrous conditions to ensure high yields and selectivity.

What industries use 5-Bromo-2,3'-bipyridine (CAS: 774-53-8)?

5-Bromo-2,3'-bipyridine (CAS: 774-53-8) is used in various industries including pharmaceuticals, where it serves as a building block for drug synthesis; in polymers, where it acts as a Lewis acid catalyst; in sensors, as a chromophore; and in semiconductors, for its unique electronic properties.

What precautions should be taken when handling 5-Bromo-2,3'-bipyridine (CAS: 774-53-8)?

When handling 5-Bromo-2,3'-bipyridine (CAS: 774-53-8), use appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work in a fume hood to minimize inhalation risks. Store it in a cool, dry place away from direct sunlight. In case of a spill, clean up using gloves and appropriate absorbent materials. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.