5-Bromo-2,3'-bipyridine(CAS: 774-53-8)

5-Bromo-2,3'-bipyridine (CAS: 774-53-8) is a crystalline solid with a molecular weight of 256.02 g/mol. It is poorly soluble in water but soluble in organic solvents such as ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophiles. It exhibits strong coordination chemistry and is often used in spectroscopic studies.

5-Bromo-2,3'-bipyridine (CAS: 774-53-8) is typically synthesized by the bromination of 2,3'-bipyridine. Common methods include the use of N-bromosuccinimide (NBS) and peracetic acid as brominating agents. The reaction is carried out in an inert solvent such as methylene chloride or dichloromethane under anhydrous conditions to ensure high yields and selectivity.

5-Bromo-2,3'-bipyridine (CAS: 774-53-8) is used in various industries including pharmaceuticals, where it serves as a building block for drug synthesis; in polymers, where it acts as a Lewis acid catalyst; in sensors, as a chromophore; and in semiconductors, for its unique electronic properties.

When handling 5-Bromo-2,3'-bipyridine (CAS: 774-53-8), use appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work in a fume hood to minimize inhalation risks. Store it in a cool, dry place away from direct sunlight. In case of a spill, clean up using gloves and appropriate absorbent materials. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.