(2R,3R)-3-[(1R)-1-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}ethyl]-4-oxo-2-azetidinyl acetate

Basic Information

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CAS Number

76855-69-1

Molecular Formula

C13H25NO4Si

Molecular Weight

287.43 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

107.0 to 110.0 deg-C

Boiling Point

358.318°C at 760 mmHg

Density

1.039

Flash Point

170.505℃

Refractive Index

1.464

Specific Rotation

51 º (c=1, chloroform)

SMILES

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CC(C1C(NC1=O)OC(=O)C)O[Si](C)(C)C(C)(C)C

InChI

InChI=1S/C13H25NO4Si/c1-8(18-19(6,7)13(3,4)5)10-11(16)14-12(10)17-9(2)15/h8,10,12H,1-7H3,(H,14,16)/t8-,10+,12-/m1/s1

InChIKey

GWHDKFODLYVMQG-UBHAPETDSA-N

LogP

2.031899999999999

Topological Polar Surface Area

64.63 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

375

Safety Information

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Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H411 Toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 9 Class 9

Synonyms & References

English

(3R,4R)-4-acetoxy-3-[(R)-1-tert-butyldimethylsilyloxyethyl]azetidin-2-one
(3R,4R)-4-Acetoxy-3-[(R)-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone
Q27266361
4-(R)acetoxy-3(R)-[1(R)t-butyldimethylsilyloxyethyl]azetidin-2-one
(3R,4R)-4-acetoxy-3-[(1R)-1-t-butyldimethylsilyloxyethyl]-2-oxoazetidine
(3R,4R)-4-acetoxy-3-[(1R)-1-t-butyldimethylsilyloxyethyl]-2-azetidinone
(3R,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone
GS-3598
(2R,3R)-3-[(1R)-1-{[tert-Butyl(dimethyl)silyl]oxy}ethyl]-4-oxo-2-azetidinyl acetate
75874VBV1X
(3R, 4R)-4-acetoxy-3-[(1R)-1-t-butyldimethylsilyloxyethyl]-2azetidinone
(3R,4R)-4-Acetoxy-3-[(R)-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone
(3R,4R)-3-[(1R)-1-t-butyldimethylsilyloxyethyl]-4-acetoxy-2-azetidinone
(3R,4R)-4-Acetoxy-3-[(R)-tert-butyldimethylsilyloxy)ethyl]-2-azetidinone
(3r,4r)-4-acetoxy-3-[(r)-1((t-butyldimethylsilyl)oxy)-ethyl]-2-azetidinone
(2R,3R)-3-((1R)-1-[[TERT-BUTYL(DIMETHYL)SILYL]OXY]ETHYL)-4-OXO-2-AZETIDINYL ACETATE
(2R,3R)-3-[(1R)-1-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}ethyl]-4-oxo-2-azetidinyl acetate
(3R, 4R)-4-acetoxy-3-[(R)-1-t-butyldimethylsilyloxyethyl]azetidin-2-one
SCHEMBL1143662
(3R,4R)-4-acetoxy-3-[(1R)-1-(tert-butyldimethylsilyloxy)ethyl]-2-oxoazetidine
AKOS024258538
(3R,4R)-4-acetoxy-3-[(1R)-1-tert-butyldimethylsilyloxyethyl)-2-azetidinone
(3R, 4R)-4-acetoxy-3-[(1R)-1-t-butyldimethylsilyloxyethyl]-2-azetidinone
(2R,3R)-3-[(1R)-1-[(tert-butyldimethylsilyl)oxy]ethyl]-4-oxoazetidin-2-yl acetate
GWHDKFODLYVMQG-UBHAPETDSA-N
MFCD00077636
92217-74-8
rel-(2R,3R)-3-((R)-1-((tert-Butyldimethylsilyl)oxy)ethyl)-4-oxoazetidin-2-yl acetate
CS-W002332
(3R,4R)-4-acetoxy-3-[(1R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone
(3R, 4R)-4-acetoxy-3-[(R)-1-t-butyldimethylsilyloxyethyl]-2 -azetidinone

MDL Number

MFCD00077636

Customs Code

2933990090

FAQ

What is (2R,3R)-3-[(1R)-1-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}ethyl]-4-oxo-2-azetidinyl acetate (CAS: 76855-69-1)?

This compound, with the CAS number 76855-69-1, is a synthetic organic molecule characterized by its complex structure containing an azetidine ring and an ester group. It is known for its potential biological activity and is often used in pharmaceutical research for its structural versatility and reactivity. The molecular formula is C12H22O5Si, and it typically appears as a white to off-white solid with a relatively high molecular weight.

What are the main uses of (2R,3R)-3-[(1R)-1-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}ethyl]-4-oxo-2-azetidinyl acetate (CAS: 76855-69-1)?

This compound is primarily used in pharmaceutical research as a building block for drug development, particularly in the synthesis of bioactive molecules. It also finds applications in organic chemistry as a versatile intermediate for creating complex structures. Due to its unique chemical properties, it is occasionally used in specialized industrial processes and research settings involving silyl ether functionalities and azetidine ring modifications.

Is (2R,3R)-3-[(1R)-1-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}ethyl]-4-oxo-2-azetidinyl acetate (CAS: 76855-69-1) safe?

Safety of this compound depends on its application and exposure conditions. It is generally considered safe when handled properly in controlled laboratory environments. However, standard safety precautions should be followed, including the use of personal protective equipment (PPE) such as gloves and goggles. It is not classified as highly toxic, but its handling should comply with general chemical safety guidelines to minimize risks.

How should (2R,3R)-3-[(1R)-1-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}ethyl]-4-oxo-2-azetidinyl acetate (CAS: 76855-69-1) be stored?

This compound should be stored in a cool, dry, and well-ventilated area, away from direct light. It is best kept in a sealed container at a temperature below 25°C to maintain stability. Due to its sensitivity to moisture and air, it is recommended to store it under an inert atmosphere, such as nitrogen, to prevent degradation.