(3-Fluorophenyl)boronic acid

Basic Information

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CAS Number

768-35-4

Molecular Formula

C6H6BFO2

Molecular Weight

139.92 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

214-218 °C

Boiling Point

271.4 °C at 760 mmHg

Density

1.2400

Flash Point

271.4 °C at 760 mmHg

SMILES

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OB(C1=CC=CC(F)=C1)O

InChI

InChI=1S/C6H6BFO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4,9-10H

InChIKey

KNXQDJCZSVHEIW-UHFFFAOYSA-N

LogP

-0.4944999999999999

Complexity

110

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

(3-Fluorophenyl)boronic acid
AKOS BRN-0105
3-FLUOROBENZENEBORONIC ACID
3-FLUORO PHENYLBORIC ACID
3-FLUOROPHENYLBORNIC ACID
3-FLUOROPHENYLBORONIC ACID
RARECHEM AH PB 0217
M-FLUOROPHENYLBORONIC ACID
3-Fluorophenylboronic Acid (contains varying amounts of Anhydride)
(3-Fluorophenyl-1-yl)boronic acid
m-fluoro-Benzeneboronic acid
3-Fluorobenzeneboronic Acid (contains varying amounts of Anhydride)
3-fluorophenyl boronic acid
(3-Fluorophenyl)Boranediol
FPBA
Boronic acid, (3-fluorophenyl)-
Boronic acid, B-(3-fluorophenyl)-
m-fluorobenzeneboronic acid
PubChem1857
3-flurophenylboronic acid
3-fluorphenylboronic acid
3-
m-Fluorophenylboronic acid
3-Fluorobenzeneboronic acid
(3-fluorophenyl)boronic acid

MDL Number

MFCD00236042

Customs Code

2931900090

FAQ

What is (3-Fluorophenyl)boronic acid (CAS: 768-35-4)?

(3-Fluorophenyl)boronic acid, with the CAS number 768-35-4, is an aromatic boronic acid derivative. Its chemical formula is C6H4FB(OH)2, featuring a fluorine atom at the 3-position of the phenyl ring. It is a white to pale yellow solid with moderate solubility in water and organic solvents. Known for its reactivity in nucleophilic substitution reactions, it is widely used in synthetic chemistry for coupling processes like the Suzuki reaction.

What are the main uses of (3-Fluorophenyl)boronic acid (CAS: 768-35-4)?

(3-Fluorophenyl)boronic acid (CAS: 768-35-4) is primarily employed in pharmaceutical research for drug development, particularly in the synthesis of anti-cancer and anti-inflammatory agents. It also serves as a key intermediate in organic synthesis, industrial chemical manufacturing, and as a catalyst in polymerization reactions. Its applications extend to research in materials science and biochemical studies due to its functional group versatility.

Is (3-Fluorophenyl)boronic acid (CAS: 768-35-4) safe?

(3-Fluorophenyl)boronic acid (CAS: 768-35-4) is generally considered safe in controlled laboratory settings. However, it may cause mild skin and eye irritation upon contact. Safety standards recommend handling with gloves, goggles, and a fume hood to minimize exposure. It is not classified as highly toxic, but proper protective measures are essential during use and disposal to ensure compliance with OSHA and EPA guidelines.

How should (3-Fluorophenyl)boronic acid (CAS: 768-35-4) be stored?

(3-Fluorophenyl)boronic acid (CAS: 768-35-4) should be stored in a cool, dry, and dark place, ideally at 2-8°C, to maintain stability. It is sensitive to moisture and light, so airtight containers with desiccants are recommended. Avoid exposure to air and heat, and keep it away from incompatible substances to prevent degradation or hazardous reactions.