(3-Fluorophenyl)boronic acid(CAS: 768-35-4)

(3-Fluorophenyl)boronic acid, with the CAS number 768-35-4, is an aromatic boronic acid derivative. Its chemical formula is C6H4FB(OH)2, featuring a fluorine atom at the 3-position of the phenyl ring. It is a white to pale yellow solid with moderate solubility in water and organic solvents. Known for its reactivity in nucleophilic substitution reactions, it is widely used in synthetic chemistry for coupling processes like the Suzuki reaction.

(3-Fluorophenyl)boronic acid (CAS: 768-35-4) is primarily employed in pharmaceutical research for drug development, particularly in the synthesis of anti-cancer and anti-inflammatory agents. It also serves as a key intermediate in organic synthesis, industrial chemical manufacturing, and as a catalyst in polymerization reactions. Its applications extend to research in materials science and biochemical studies due to its functional group versatility.

(3-Fluorophenyl)boronic acid (CAS: 768-35-4) is generally considered safe in controlled laboratory settings. However, it may cause mild skin and eye irritation upon contact. Safety standards recommend handling with gloves, goggles, and a fume hood to minimize exposure. It is not classified as highly toxic, but proper protective measures are essential during use and disposal to ensure compliance with OSHA and EPA guidelines.

(3-Fluorophenyl)boronic acid (CAS: 768-35-4) should be stored in a cool, dry, and dark place, ideally at 2-8°C, to maintain stability. It is sensitive to moisture and light, so airtight containers with desiccants are recommended. Avoid exposure to air and heat, and keep it away from incompatible substances to prevent degradation or hazardous reactions.