Methyl 1-(triphenylmethyl)-2-aziridinecarboxylate

Basic Information

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CAS Number

76357-18-1

Molecular Formula

C23H21NO2

Molecular Weight

343.43 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

132 °C

SMILES

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COC(=O)C1CN1C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChI=1S/C23H21NO2/c1-26-22(25)21-17-24(21)23(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20/h2-16,21H,17H2,1H3

InChIKey

QGSITPKXYQEFIR-UHFFFAOYSA-N

LogP

3.8357000000000028

Topological Polar Surface Area

29.310000000000002 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

427

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

MFCD01863736
Methyl (R)-1-Tritylaziridine-2-carboxylate
M1927
NSC-157268
METHYL 1-(TRIPHENYLMETHYL)AZIRIDINE-2-CARBOXYLATE
1-Trityl-aziridine-2-carboxylic acid methyl ester
Methyl 1-(Triphenylmethyl)-2-aziridinecarboxylate
A915124
Bis(dimethylamino)?phosphoryl Chloride
SY099276
MFCD09878842
BDA35718
Methyl (S)-1-Tritylaziridine-2-carboxylate
QGSITPKXYQEFIR-MQNHUJCZSA-N
1-Trityl-2-aziridinecarboxylic acid methylester
A906591
MFCD09991705
Methyl 1-Trityl-2-aziridinecarboxylate
QGSITPKXYQEFIR-FHZUCYEKSA-N
BS-23594
C23H21NO2
NSC157268
AKOS015840554
76357-18-1
A838335
CS-0199806
methyl 1-tritylaziridine-2-carboxylate
1-Trityl-2-aziridinecarboxylic Acid Methyl Ester
SY097000
SCHEMBL2298098
(R)-Methyl 1-tritylaziridine-2-carboxylate

MDL Number

MFCD09991705

FAQ

What are the physical and chemical properties of Methyl 1-(triphenylmethyl)-2-aziridinecarboxylate (CAS: 76357-18-1)?

Methyl 1-(triphenylmethyl)-2-aziridinecarboxylate (CAS: 76357-18-1) is a crystalline compound with a molecular weight of approximately 536.48 g/mol. It has low water solubility but is soluble in organic solvents such as methanol and acetonitrile. The compound is known for its reactivity, particularly towards nucleophiles and electrophiles, making it useful in organic synthesis. It reacts efficiently under mild conditions, exhibiting good stability in the solid state.

How is Methyl 1-(triphenylmethyl)-2-aziridinecarboxylate (CAS: 76357-18-1) typically synthesized?

Methyl 1-(triphenylmethyl)-2-aziridinecarboxylate (CAS: 76357-18-1) is typically synthesized by the reaction of methyl aziridinylcarboxylate with triphenylmethanol in the presence of a catalytic amount of a Lewis acid such as aluminum trichloride. The reaction yields a high selectivity and a good yield of the product under mild conditions, making it a viable method for industrial production.

What industries use Methyl 1-(triphenylmethyl)-2-aziridinecarboxylate (CAS: 76357-18-1)?

Methyl 1-(triphenylmethyl)-2-aziridinecarboxylate (CAS: 76357-18-1) is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of drug molecules, and in the polymer industry, where it can be used as a functional monomer for making advanced materials. Additionally, it is utilized in sensor technology and semiconductor manufacturing for its unique chemical reactivity.

What precautions should be taken when handling Methyl 1-(triphenylmethyl)-2-aziridinecarboxylate (CAS: 76357-18-1)?

When handling Methyl 1-(triphenylmethyl)-2-aziridinecarboxylate (CAS: 76357-18-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be washed down with water. Always refer to the safety data sheet (SDS) for detailed information on handling and disposal procedures.