(1R)-1-(4-Chlorophenyl)ethanol

Basic Information

View in Editor

CAS Number

75968-40-0

Molecular Formula

C8H9ClO

Molecular Weight

156.61 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

240.6±15.0℃ at 760 mmHg

Density

1.158 g/mL at 25 °C

Refractive Index

n20/D 1.544

Specific Rotation

49 º (c=1.6 in chloroform)

SMILES

View in Editor

CC(C1=CC=C(C=C1)Cl)O

InChI

InChI=1S/C8H9ClO/c1-6(10)7-2-4-8(9)5-3-7/h2-6,10H,1H3/t6-/m1/s1

InChIKey

MVOSNPUNXINWAD-ZCFIWIBFSA-N

LogP

2.3933

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

97.4

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H318 Causes serious eye damage
Serious eye damage/eye irritation

Synonyms & References

English

SC1272
(1R)-1-(4-chlorophenyl)ethanol
(r)-1-(4-chlorophenyl) ethanol
CS-W008498
75968-40-0
(R)-4-Chloro-alpha-methylbenzyl Alcohol
BAA51770
AKOS012670049
DS-17633
SCHEMBL1253041
(R)-1-(4-chlorophenyl)ethan-1-ol
MVOSNPUNXINWAD-ZCFIWIBFSA-N
(R)-1-(4-Chlorophenyl)ethanol
(R)-4-Chloro- alpha -methylbenzyl alcohol
(R)-4-Chloro-a-methylbenzyl alcohol
(1R)-1-(4-chlorophenyl)ethan-1-ol
(R)-1-(4-chlorophenyl)ethanol;(R)-4-Chloro-alpha-methylbenzyl Alcohol
(R)-4-CHLORO-ALPHA-METHYLBENZYLALCOHOL
EN300-253239
(R)-4-Chloro-alpha-methylbenzyl alcohol, 95%
MFCD06797295
A821996
AMY10616
A9640
(R)-(+)-1-(4-chlorophenyl)-1-ethanol
(R)-(+)-1-(4-chlorophenyl)ethan-1-ol
(R)-1-(p-chlorophenyl)-1-ethanol
(R)-4-CHLORO-ALPHA-METHYLBENZYL ALCOHOL
PubChem14249
(R)-1-(p-Chlorophenyl)ethanol
(R)-1-(4-Chloro-phenyl)-ethanol

MDL Number

MFCD06797295

Customs Code

2906299090

FAQ

What are the physical and chemical properties of (1R)-1-(4-Chlorophenyl)ethanol (CAS: 75968-40-0)?

(1R)-1-(4-Chlorophenyl)ethanol is a colorless to pale yellow liquid with a molecular weight of approximately 164.63 g/mol. Its solubility in water is low (0.1 g/100 mL at 20°C), but it is more soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophiles and electrophiles, and it exhibits good stability under normal conditions but degrades under basic conditions.

How is (1R)-1-(4-Chlorophenyl)ethanol (CAS: 75968-40-0) typically synthesized?

(1R)-1-(4-Chlorophenyl)ethanol can be synthesized using a Grignard reaction where 4-chlorophenyl magnesium bromide is reacted with ethanol. The reaction is typically carried out in anhydrous diethyl ether under inert atmosphere. This method provides good yield and selectivity, although the use of organomagnesium reagents requires careful handling to avoid fire hazards.

What industries use (1R)-1-(4-Chlorophenyl)ethanol (CAS: 75968-40-0)?

(1R)-1-(4-Chlorophenyl)ethanol is used in the pharmaceutical industry for the synthesis of certain drugs due to its unique structural properties. It is also employed in the detergent and cosmetics industry as a raw material. Additionally, it has applications in the polymer and sensor industries, contributing to the development of new materials and sensing technologies.

What precautions should be taken when handling (1R)-1-(4-Chlorophenyl)ethanol (CAS: 75968-40-0)?

When handling (1R)-1-(4-Chlorophenyl)ethanol, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat to avoid skin contact and eye irritation. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, it should be handled using appropriate spill kits or collected and disposed of as per local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.