Compound Q&A
How is (1R)-1-(4-Chlorophenyl)ethanol (CAS: 75968-40-0) typically synthesized?
Answer
(1R)-1-(4-Chlorophenyl)ethanol can be synthesized using a Grignard reaction where 4-chlorophenyl magnesium bromide is reacted with ethanol. The reaction is typically carried out in anhydrous diethyl ether under inert atmosphere. This method provides good yield and selectivity, although the use of organomagnesium reagents requires careful handling to avoid fire hazards.
About
CAS No
75968-40-0
English Name
(1R)-1-(4-Chlorophenyl)ethanol
Molecular Formula
C8H9ClO
Molecular Weight
156.61 g/mol
SMILES
CC(C1=CC=C(C=C1)Cl)O
InChIKey
MVOSNPUNXINWAD-ZCFIWIBFSA-N
Last Updated: 2025-10-13 19:39
