6-aminopyridine-2-sulfonamide

Basic Information

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CAS Number

75903-58-1

Molecular Formula

C5H7N3O2S

Molecular Weight

173.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

455.2±55.0°C at 760 mmHg

SMILES

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C1=CC(=NC(=C1)S(=O)(=O)N)N

InChI

InChI=1S/C5H7N3O2S/c6-4-2-1-3-5(8-4)11(7,9)10/h1-3H,(H2,6,8)(H2,7,9,10)

InChIKey

GFQVENVAWVSTNP-UHFFFAOYSA-N

LogP

-0.6887999999999999

Topological Polar Surface Area

99.07 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

220

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

DTXSID201308409
C76427
DS-8691
2-Pyridinesulfonamide,6-amino-(9CI)
SB53445
EN300-276714
6-Amino-2-pyridinesulfonamide
GFQVENVAWVSTNP-UHFFFAOYSA-N
CS-0158099
SCHEMBL17647899
A923258
GS1214
MFCD18816592
6-Aminopyridine-2-sulfonamide
AKOS022638672
75903-58-1
2-Pyridinesulfonamide,6-amino-
6-amino-2-Pyridinesulfonamide
AK174302

MDL Number

MFCD18816592

FAQ

What are the physical and chemical properties of 6-aminopyridine-2-sulfonamide (CAS: 75903-58-1)?

6-Aminopyridine-2-sulfonamide is a crystalline solid with a molecular weight of approximately 225.23 g/mol. It has a solubility of about 10 mg/mL in water and is slightly soluble in organic solvents. Chemically, it is reactive towards nucleophiles, making it suitable for various functional group transformations.

How is 6-aminopyridine-2-sulfonamide (CAS: 75903-58-1) typically synthesized?

6-Aminopyridine-2-sulfonamide is typically synthesized by reacting 6-chloropyridine-2-sulfonamide with sodium azide in an aprotic solvent such as N,N-dimethylformamide (DMF) in the presence of a base like sodium hydroxide. The reaction yields the amide via an azide intermediate.

What industries use 6-aminopyridine-2-sulfonamide (CAS: 75903-58-1)?

6-Aminopyridine-2-sulfonamide finds applications in the pharmaceutical industry due to its potential as a precursor for drug synthesis. It is also used in the development of sensors and in the synthesis of certain polymers and semiconductors.

What precautions should be taken when handling 6-aminopyridine-2-sulfonamide (CAS: 75903-58-1)?

Handle 6-aminopyridine-2-sulfonamide in a well-ventilated fume hood due to its potential for inhalation hazards. Wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store it in a cool, dry place away from oxidizers and heat sources. In case of spill, clean up using appropriate safety protocols and consult the Safety Data Sheet (SDS) for further guidance.