3-methoxy-5-nitro-pyridin-2-ol

Basic Information

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CAS Number

75710-99-5

Molecular Formula

C6H6N2O4

Molecular Weight

170.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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COC1=CC(=CNC1=O)[N+](=O)[O-]

InChI

InChI=1S/C6H6N2O4/c1-12-5-2-4(8(10)11)3-7-6(5)9/h2-3H,1H3,(H,7,9)

InChIKey

JDHPYWKDVDFUDW-UHFFFAOYSA-N

LogP

1.22720

Complexity

286

Synonyms & References

English

3-Methoxy-5-Nitro-2-Pyridone
EN300-313594
MFCD06658463
3-Methoxy-5-nitropyridin-2(1H)-one
75710-99-5
SB53230
3-methoxy-5-nitro-1H-pyridin-2-one
SCHEMBL11325306
2-pyridinol, 3-methoxy-5-nitro-
DTXSID20634326
FT-0600060
AM804324
3-Methoxy-5-nitropyridin-2-ol
AS-36590
A838494
AKOS006293130
3-Methoxy-5-nitro-pyridin-2-ol (~90%)
Z2678251421
3-Methoxy-5-nitro-pyridin-2-ol
SCHEMBL3648669
CS-0209087
2-Hydroxy-3-methoxy-5-nitropyridine

MDL Number

MFCD06658463

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5)?

3-Methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5) is a crystalline solid with a molecular weight of approximately 184.11 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. The compound is moderately reactive, showing reactivity towards nucleophiles and reducing agents. It is also prone to decomposition under heating conditions.

How is 3-methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5) typically synthesized?

3-Methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5) can be synthesized through the nitration of 3-methoxy-pyridin-2-ol followed by reduction of the nitro group. Commonly, nitration is carried out using concentrated nitric acid and sulfuric acid, and reduction is achieved using hydrogen gas in the presence of a catalyst like palladium on carbon. The overall yield of the product is typically around 70-80%, depending on the conditions.

What industries use 3-methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5)?

3-Methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a precursor for the production of functional polymers. Additionally, it is used in the synthesis of sensors and as a reducing agent in analytical chemistry.

What precautions should be taken when handling 3-methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5)?

When handling 3-methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation of potential fumes. Spills should be cleaned up with care using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.