3-methoxy-5-nitro-pyridin-2-ol(CAS: 75710-99-5)

3-Methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5) is a crystalline solid with a molecular weight of approximately 184.11 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. The compound is moderately reactive, showing reactivity towards nucleophiles and reducing agents. It is also prone to decomposition under heating conditions.

3-Methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5) can be synthesized through the nitration of 3-methoxy-pyridin-2-ol followed by reduction of the nitro group. Commonly, nitration is carried out using concentrated nitric acid and sulfuric acid, and reduction is achieved using hydrogen gas in the presence of a catalyst like palladium on carbon. The overall yield of the product is typically around 70-80%, depending on the conditions.

3-Methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a precursor for the production of functional polymers. Additionally, it is used in the synthesis of sensors and as a reducing agent in analytical chemistry.

When handling 3-methoxy-5-nitro-pyridin-2-ol (CAS: 75710-99-5), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation of potential fumes. Spills should be cleaned up with care using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.