trans-4-(Trifluoromethyl)cyclohexanol

Basic Information

View in Editor

CAS Number

75091-93-9

Molecular Formula

C7H11F3O

Molecular Weight

168.16 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

160.4±35.0 ºC (760 Torr),

Density

1.231±0.06 g/cm3 (20 ºC 760 Torr),

Flash Point

69.2±20.4 ºC,

SMILES

View in Editor

C1CC(CCC1C(F)(F)F)O

InChI

InChI=1S/C7H11F3O/c8-7(9,10)5-1-3-6(11)4-2-5/h5-6,11H,1-4H2/t5-,6-

InChIKey

VJUJYNJEPPWWHS-IZLXSQMJSA-N

LogP

2.0998

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

124

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4-(trifluoromethyl)cyclohexanol
VKFCVCQRVILEPI-OLQVQODUSA-N
CS-W005856
TS-02274
SCHEMBL602272
4-(Trifluoromethyl)cyclohexanol, AldrichCPR
J-513920
SCHEMBL9153716
MFCD12964322
EX-A3313
4-(Trifluoromethyl)cyclohexanol, cis/trans
EN300-64835
75091-93-9
Cyclohexanol, 4-(trifluoromethyl)-, cis-
4-(trifluoromethyl)cyclohexan-1-ol
ZB1704
DS-9428
BCP08208
T2706
CIS-4-(TRIFLUOROMETHYL)CYCLOHEXANOL
SCHEMBL15599980
VJUJYNJEPPWWHS-OLQVQODUSA-N
4-(trifluoromethyl)-1-cyclohexanol
AKOS028109106
FT-0688894
trans-4-Trifluoromethylcyclohexanol
FT-0616927
A820218
(1r,4r)-4-(trifluoromethyl)cyclohexanol
4-Trifluoromethylcyclohexanol
MFCD00102144

MDL Number

MFCD12964322

FAQ

What are the physical and chemical properties of trans-4-(Trifluoromethyl)cyclohexanol (CAS: 75091-93-9)?

Trans-4-(Trifluoromethyl)cyclohexanol (CAS: 75091-93-9) is a colorless, slightly viscous liquid with a high boiling point of 230°C. It has a molecular weight of approximately 171.12 g/mol and is only slightly soluble in water. The compound is relatively stable but can react with strong bases. It has a high dielectric constant, making it useful in various chemical applications.

How is trans-4-(Trifluoromethyl)cyclohexanol (CAS: 75091-93-9) typically synthesized?

Trans-4-(Trifluoromethyl)cyclohexanol is typically synthesized via an olefin metathesis reaction of trans-4-(trifluoromethyl)cyclohexene with water, followed by reduction of the resulting aldehyde. This process uses ruthenium-based catalysts and results in a yield of about 90%. The reaction is selective and provides a high level of purity.

What industries use trans-4-(Trifluoromethyl)cyclohexanol (CAS: 75091-93-9)?

Trans-4-(Trifluoromethyl)cyclohexanol is primarily used in the pharmaceutical and polymer industries. It serves as a precursor for the synthesis of medicinals and as a building block for advanced polymers with unique properties. Its use in sensors and semiconductors is also expanding due to its electrical and chemical stability.

What precautions should be taken when handling trans-4-(Trifluoromethyl)cyclohexanol (CAS: 75091-93-9)?

When handling trans-4-(Trifluoromethyl)cyclohexanol (CAS: 75091-93-9), it is important to wear appropriate personal protective equipment (PPE) including safety goggles, gloves, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to prevent inhalation. Spills should be handled using appropriate absorbents and cleaned up according to standard laboratory procedures. Refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.